Abstract
Chronic kidney disease (CKD) involves a series of inflammatory events that induce fibrosis of the renal parenchyma. No one knows why these processes are triggered even in the absence of microbial antigens or other proteins foreign to the body. The discovery of toll-like receptors (TLRs) and inflamassomas, as well as its interaction with the NF-ºB system, can contribute to solve this issue…