CV Lattes
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Universidade Federal de São Paulo (UNIFESP). Campus Diadema. Instituto de Ciências Ambientais, Químicas e Farmacêuticas (ICAQF) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduation at Biologia - Bacharelado from Universidade Presbiteriana Mackenzie (2005), graduation at Biologia - Licenciatura from Universidade Presbiteriana Mackenzie (2004), master's at Physiology from Universidade de São Paulo (2008) and doctorate at Physiology from Universidade de São Paulo (2013). Has experience in Physiology, focusing on Endocrinal Physiology, acting on the following subjects: expressão gênica, cauda poli-a, iodo, regulação pós-transcricional and tratamento agudo. (Source: Lattes Curriculum)
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Endocrine Disruptors (EDs) are synthetic or natural compounds that interfere with the endocrine system and induce harmful effects to the organism. Even though, these deleterious effects depend on the dose and the period of exposure to EDs. In fact, several studies indicated increased amounts of EDs in human samples as well as in the environment that are mainly associated to the extensive …
Endocrine disruptors are chemical substances that interfere with endocrine function, producing adverse effects on growth, development, reproduction, and metabolism, with systemic repercussions to varying degrees depending on the time of exposure and the developmental stage at which the individual is exposed. In recent years, different experimental models have been used to better understan…
OCPs, such as DDT, widely used during World War II, were banned in the 1970s in developed countries and in 2009 in Brazil, but are still widely used in several countries to combat the malaria vector, and are even used illegally in the country. DDT and its metabolites, such as DDE, are highly stable, persistent in the environment, and accumulate in adipose tissue in humans and animals. In …
PCBs (polychlorinated biphenyls) are flame retardant compounds widely used as lubricants in the industry and in several electronic devices. The use of PCBs was banned over 25 years ago, however, they are highly persistent in the environment and remain in the food chain until this day. PCBs are lipophilic, concentrate in the adipose tissue and serum, and their biological half-life in human…
(Only some records are available in English at this moment)
Endocrine disruptors are synthetic or natural compounds that negatively affects the endocrine system function. Triclosan (TCS) is an antimicrobial chemical used in several products, as personal care products, food, pesticides, plastics, rubbers and industrial additive. TCS is widely found in the environment, and it has already been found in breast milk, plasma and urine samples of humans.…
Nitrate inhibits the iodide uptake mediated by the sodium-iodide symporter (NIS) in the thyrocytes. Therefore, this endocrine disruptor interferes with thyroid hormone biosynthesis. It is worth noting that nitrate levels in the food and water have significantly increased in the last decades, due to the exacerbated use of nitrogen fertilizers. In fact, several studies have associated the c…
Perchlorate is a widespread contaminant present in irrigation water, soil and food. This anion inhibits the iodide uptake mediated by the sodium-iodide symporter (NIS) in thyrocytes. Several studies have shown that besides its inhibitory action, perchlorate is also transported by NIS in the thyroid cells. Therefore, this anion interferes with the thyroid hormone synthesis and impairs the …
(Only some records are available in English at this moment)
Both iodine deficiency (ID) and excess (IE) impair thyroid hormones synthesis, causing serious consequences especially during fetal/neonatal periods. Our previous data indicated that pregnant rats exposed to IE induced hypothyroidism in the adult male rats offspring through epigenetic mechanisms. This study aims to investigate the effects of IE exposure on the development and differentiat…
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| 4 / 4 | Ongoing scholarships in Brazil |
| 6 / 4 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 13 / 11 | All research grants and scholarships |
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