Abstract
Polycythemia vera (PV), essential thrombocythemia (ET) and myelofibrosis (MF) are Chronic Myeloproliferative Neoplasms (NMPC) which are characterized by presenting accumulation of erythrocytes, leukocytes, and morphologically normal platelets and their precursors. Little is known about the cellular and molecular mechanisms involved in the pathophysiology and progression of these disorders…