CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Tupã. Faculdade de Ciências e Engenharia (Institutional affiliation from the last research proposal) Birthplace: Brazil
Associated Professor at Department of Biosystem Engineering, School of Sciences and Engineering, Campus of Tupã - São Paulo State University (Unesp). Graduated at Farmacy/Biochemistry at School of Pharmaceutical Sciences, Araraquara, São Paulo State University (2007). Master's degree in Biotechnology in 2009 and P.h.D. in Biotechnology at Institute of Chemistry, Araraquara, Unesp. Has experience in Biochemistry, focusing on peptide membrane interactions, acting on the following subjects: EPR, DEER, peptides, solid phase peptide synthesis and CD, InfraRed, UV/Vis and Fluorescence spectroscopies. Performed a doctorate-sandwich for 9 months at the Department of Chemistry and Biochemistry, Miami University - Oxford, OH - USA, with emphasis on Electronic Paramagnetic Resonance (DEER). Post-doctorate in the Department of Physics of the Faculty of Philosophy, Sciences and Letters of Ribeirão Preto - University of São Paulo (FFCLRP - USP), in Biophysics and pulsed RPE area. He has experience in the field of Biochemistry and the main studies are the interactions between peptide/protein and membrane mimetics using the techniques of solid phase peptide synthesis (SPFS), Mass Spectrometry and various chromatographic and spectroscopic techniques such as HPLC, UV- VIs, CD, Fluorescence, EPR, NMR and FTIR. Currently works with application of antimicrobial peptides in animal and plant production. He is the leader in the research group Peptides: Synthesis, Optimization and Applied Studies - PeSEAp (http://dgp.cnpq.br/dgp/espelhogrupo/8928581274143158). (Source: Lattes Curriculum)
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Antimicrobial resistance is a worldwide threat and demands urgent actions in different re-search areas for development of strategies to proper combat it. Some studies suggest that, until 2050, uncontrolled diseases caused by microorganism can lead 10 million people to death, which will overcome the deaths caused by cancer at the same period. In this way, antimicrobial peptides (AMP) are s…
Antimicrobial resistance is a worldwide threat and demands urgent actions in different re-search areas for development of strategies to proper combat it. Some studies suggest that, until 2050, uncontrolled diseases caused by microorganism can lead 10 million people to death, which will overcome the deaths caused by cancer at the same period. In this way, antimicrobi-al peptides (AMP) are …
During the past decades, a great number of antimicrobial peptides (AMPs) have been identified from a variety of species of vertebrates and invertebrates, such as magainin, aurein, cecropin, ceratotoxin, among others. Especially, the antimicrobial peptide Ctx(Ile21)-Ha, extracted and isolated from the skin secretion of an arboreal South American frog (Hypsiboas albopunctatus), has been stu…
During the past decades, a great number of antimicrobial peptides (AMPs) have been identified from a variety of species of vertebrates and invertebrates, such as magainin, aurein, cecropin, ceratotoxin, among others. Especially, the antimicrobial peptide Ctx(Ile21)-Ha, extracted and isolated from the skin secretion of an arboreal South American frog (Hypsiboas albopunctatus), has been stu…
During the past decades, a great number of antimicrobial peptides (AMPs) have been identified from a variety of species of vertebrates and invertebrates, such as magainin, aurein, cecropin, ceratotoxin, among others. Especially, the antimicrobial peptide Ctx(Ile21)-Ha, extracted and isolated from the skin secretion of an arboreal South American frog (Hypsiboas albopunctatus), has been stu…
(Only some records are available in English at this moment)
Nowadays, the prevalence of diabetes mellitus in the world is high, where its emergence is associated with secondary complications, in addition to the role of highly industrialized foods in the diet, directly impacting global health. The main risk factors for developing diabetes are genetic predisposition, inadequate diet and deficiency in insulin production. It should be noted that, desp…
The effectiveness of conventional drugs against some emerging pathogens has drastically decreased and they can cause undesirable and even lethal side effects. This occurred because, over time, the disorderly use of these antibiotics caused serious problems related to public health, such as antimicrobial resistance. In view of this, the antimicrobial peptide Ctx(Ile21)-Ha has been proving …
Antibiotics for veterinary use are essential for the control, prevention and treatment of a range of infectious diseases. Antimicrobial additives can assist in the absorption of nutrients, inhibiting the growth of pathogenic microorganisms and increasing the performance of these animals. Over time, the indiscriminate use of these molecules has strongly unbalanced the balance of the intest…
Studies on the cyclic peptides structures have been advancing significantly, and may help in several areas of scientific research. Specifically, the cyclic peptide Pohlianina A, belonging to the Jatropha genus and classified as an orbitid, fits into the area of natural products with promising biological activities. Thus, in order to analyze different conformations of this molecule and obt…
Peptides are considered less toxic than small molecules. However, one drawback is their lack of stability, particularly in the gastrointestinal tract, due to natural degradation by proteases and acidic environment. To overcome this obstacle, we will use disulphide-stabilized peptides derived from the repertoire of Nature. For example, Violaceae family plants are a rich source of cyclic cy…
In order to exert their varied biological activity against different microorganisms, antimicrobial peptides need to present different physicochemical characteristics such as helicity, amphipathicity, hydrophobicity and cationicity. These properties, when integrated and modulated, can promote an increase or a decrease in its biological activity. In addition, it is known that the N-terminal…
(Only some records are available in English at this moment)
| 2 / 2 | Ongoing research grants |
| 5 / 4 | Completed research grants |
| 3 / 3 | Ongoing scholarships in Brazil |
| 12 / 10 | Completed scholarships in Brazil |
| 22 / 19 | All research grants and scholarships |
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