CV Lattes
ResearcherID
ORCID
Universidade de São Paulo (USP). Faculdade de Zootecnia e Engenharia de Alimentos (FZEA) (Institutional affiliation from the last research proposal) Birthplace: Brazil
bachelor's at Ciências Biológicas from Pontifícia Universidade Católica do Rio Grande do Sul (2004) and master's at Genética e Toxicologia Aplicada from Universidade Luterana do Brasil (2007). Has experience in Genetics, focusing on Genetics, acting on the following subjects: toxicologia, genética, marcadores moleculares, biomonitoramento and teste cometa. (Source: Lattes Curriculum)
| News published in Agência FAPESP Newsletter about the researcher |
| TITULO |
| Articles published in other media outlets (0 total): |
| More itemsLess items |
| VEICULO: TITULO (DATA) |
| VEICULO: TITULO (DATA) |
Although reproductive processes are modulated by mechanisms involving endocrine cell communication, recently molecular mechanisms complementary to the endocrine ones have also been related to reproductive functions. Similar to endocrine hormone communication, there are moleculesimportant to the reproductive processes that act in a paracrine way, being carried primarily through extracellul…
In vitro production of embryos (IVP) is widely used in humans and animals as alternatives to infertility problems and a tool to increase the production efficiency of livestock animals, especially in cattle. Since its beginning, IVP relied on the constant evolution of cell culture media composition based on the observed composition of reproductive biofluids. Extracellular vesicles (EVs) ar…
In vitro production of embryos (IVP) is widely used in humans and animals as alternatives to infertility problems and a tool to increase the production efficiency of livestock animals, especially in cattle. Since its beginning, IVP relied on the constant evolution of cell culture media composition based on the observed composition of reproductive biofluids. Extracellular vesicles (EVs) ar…
(Only some records are available in English at this moment)
Dr. Bouma has extensive experience in the study of trophoblast formation in ruminants. In its most recent studies, the CRISPR / CAS9 technique is used as a tool for genome molecular manipulation to understand pathways involved with normal or abnormal placental formation. Our intention with the coming of Dr. Bouma is to implement strategies to study the effects of in vitro embryo productio…
In 30 years, the global population growth associated with the high demand for animal protein will claim for a high evolution of the beef cattle production indexes. The increase in livestock efficiency is based on several factors, among which the reproductive index of the herd represents a great intercession of this segment. Reproductive biotechnologies are tools capable of optimizing the …
In-vitro embryo production is an important tool for increasing productivity in females for genetic improvement of herds. Brazil is a world leader in this technology, and has begun exporting this knowledge in recent years. However, the follicular puncture (OPU - ovum pick-up) procedure used in collection of oocytes can cause important ovarian lesions, that are often irreversible. This comp…
(Only some records are available in English at this moment)
The search for reproductive biotechniques has become a mean to achieve an efficient increase in the productivity of cattle herds. Among them, in vitro embryo production stands out, a biotechnique widely used in Brazil. With this, the importance of improving this technique arises, through the study of the cellular mechanisms involved in the intercellular communication within the follicular…
Reproductive biotechnologies such as in vitro embryo production accelerate genetic improvement, but its success is directly linked to the ability to mimic the in vivo environment. Among the events that occur during follicular maturation and oocyte growth is the intercellular communication in the follicular environment and consequently the transfer of biomolecules between somatic cells and…
Maternal recognition of pregnancy in ruminants refers to the requirement for the conceptus to secrete Interferon Tau (IFNT) that acts on the uterus and extrauterine tissue as well as immune cells to help pregnancy maintenance. During this period, the compounds secreted by the embryo create an immunotolerant-like environment towards the embryo. One characteristic of the immune response is …
(Only some records are available in English at this moment)
In vitro production of bovine embryos (IVP) is a technique capable of increasing the number of offspring for each donor leading to increased genetic progress of the offspring. However, the technique still have some limitations including the cell culture medium. Therefore, new technologies are being developed to mimic the in vivo produced embryos. Small extracellular vesicles (EVs) secret…
In vitro embryo production (IVP) is a technique of high relevance and use, however it still has some limitations that end up reducing its efficiency, such as low development rate to the blastocyst stage and low pregnancy rates. Embryos obtained from IVP still differ from embryos produced in vivo in epigenetic factors, which can interfere with the establishment of pregnancy and also the he…
(Only some records are available in English at this moment)
Extracellular vesicles (EVs) are nanoparticles secreted by different cell types in body fluids and carry bioactive materials (lipids, proteins, miRNAs) as a means of intercellular communication. Recent studies have demonstrated the role of EVs as biomarkers or as supplements to culture medium. However, the challenge is to define an accurate and reliable protocol for the EVs isolation due…
The in vitro embryo production technique (IVEP) was developed almost 40 years ago and still has some limitations that need to be overtaking, such as some diseases that can compromise the animals after birth. During this time the science and technology also had great advances that could be applied to improve IVEP. One of this is 3D bioprinting, a technique that allow the printing of struct…
Assisted reproductive techniques (ART) are alternatives to infertility and to increase the production of domestic animals. Although these techniques are widely used, they can cause negative consequences since early pregnancy until adult life. Attempts to mimic in vivo environment are applied to improve problems caused by ARTs. Extracellular vesicles (EVs) secreted by cells are important t…
| 4 / 4 | Ongoing research grants |
| 8 / 8 | Completed research grants |
| 6 / 6 | Ongoing scholarships in Brazil |
| 9 / 9 | Completed scholarships in Brazil |
| 1 / 1 | Ongoing scholarships abroad |
| 2 / 2 | Completed scholarships abroad |
| 31 / 31 | All research grants and scholarships |
| Associated processes | |