CV Lattes
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ORCID
Universidade de São Paulo (USP). Faculdade de Zootecnia e Engenharia de Alimentos (FZEA) (Institutional affiliation from the last research proposal) Birthplace: Brazil
bachelor's at Ciências Biológicas from Pontifícia Universidade Católica do Rio Grande do Sul (2004) and master's at Genética e Toxicologia Aplicada from Universidade Luterana do Brasil (2007). Has experience in Genetics, focusing on Genetics, acting on the following subjects: toxicologia, genética, marcadores moleculares, biomonitoramento and teste cometa. (Source: Lattes Curriculum)
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Although reproductive processes are modulated by mechanisms involving endocrine cell communication, recently molecular mechanisms complementary to the endocrine ones have also been related to reproductive functions. Similar to endocrine hormone communication, there are moleculesimportant to the reproductive processes that act in a paracrine way, being carried primarily through extracellul…
In vitro production of embryos (IVP) is widely used in humans and animals as alternatives to infertility problems and a tool to increase the production efficiency of livestock animals, especially in cattle. Since its beginning, IVP relied on the constant evolution of cell culture media composition based on the observed composition of reproductive biofluids. Extracellular vesicles (EVs) ar…
In vitro production of embryos (IVP) is widely used in humans and animals as alternatives to infertility problems and a tool to increase the production efficiency of livestock animals, especially in cattle. Since its beginning, IVP relied on the constant evolution of cell culture media composition based on the observed composition of reproductive biofluids. Extracellular vesicles (EVs) ar…
(Only some records are available in English at this moment)
Dr. Bouma has extensive experience in the study of trophoblast formation in ruminants. In its most recent studies, the CRISPR / CAS9 technique is used as a tool for genome molecular manipulation to understand pathways involved with normal or abnormal placental formation. Our intention with the coming of Dr. Bouma is to implement strategies to study the effects of in vitro embryo productio…
In 30 years, the global population growth associated with the high demand for animal protein will claim for a high evolution of the beef cattle production indexes. The increase in livestock efficiency is based on several factors, among which the reproductive index of the herd represents a great intercession of this segment. Reproductive biotechnologies are tools capable of optimizing the …
In-vitro embryo production is an important tool for increasing productivity in females for genetic improvement of herds. Brazil is a world leader in this technology, and has begun exporting this knowledge in recent years. However, the follicular puncture (OPU - ovum pick-up) procedure used in collection of oocytes can cause important ovarian lesions, that are often irreversible. This comp…
(Only some records are available in English at this moment)
Beef production efficiency and reproductive system are directly influenced by nutritional factors. The factors that regulate ovarian function, embryonic quality, and the establishment of the pregnancy can be affected by energy level and body condition. During the period of pre-implantation, the embryo migrates from the oviduct to the uterus in cattle. At this time, about 40% of embryonic …
A large proportion of high-production dairy cows exhibit negative energy balance (NEB) in the postpartum period. The mobilization of body reserves during this period aims to meet the energy demands of milk production. This mobilization increases metabolites such as non-esterified fatty acids (NEFAs) and beta-hydroxybutyrate (BHB). These metabolites are toxic to reproductive cells when in …
The search for reproductive biotechniques has become a mean to achieve an efficient increase in the productivity of cattle herds. Among them, in vitro embryo production stands out, a biotechnique widely used in Brazil. With this, the importance of improving this technique arises, through the study of the cellular mechanisms involved in the intercellular communication within the follicular…
(Only some records are available in English at this moment)
Reproductive biotechnologies such as in vitro embryo production accelerate genetic improvement, but its success is directly linked to the ability to mimic the in vivo environment. Among the events that occur during follicular maturation and oocyte growth is the intercellular communication in the follicular environment and consequently the transfer of biomolecules between somatic cells and…
(Only some records are available in English at this moment)
Embryo development occurs within a dynamic environment, characterized by molecular exchanges between the embryo and maternal structures. However, this scenario is often disrupted in vitro, where embryos can also be cultured. Consequently, the inability to fully replicate the in vivo environment likely accounts for the reduced developmental potential observed in in vitro-produced embryos, …
Dairy cows milk production has increased over the past decade as a result of intense genetic selection. However, the advances in genetic selection of dairy herds did not come with an improvement of reproductive parameters. Negative energy balance (NEB) during postpartum period is important risk factor in the establishment of reproductive failure in high producing dairy cows and has signif…
The livestock industry in Brazil holds a prominent global position, with a significant focus on improving efficiency. Reproductive biotechnologies, especially in vitro embryo production, have gained attention for enhancing productivity. Co-culturing with bovine oviductal epithelial cells has shown promise, as they interact with embryos and oviductal fluid, containing extracellular vesicle…
Extracellular vesicles (EVs) are nanoparticles secreted by different cell types in body fluids and carry bioactive materials (lipids, proteins, miRNAs) as a means of intercellular communication. Recent studies have demonstrated the role of EVs as biomarkers or as supplements to culture medium. However, the challenge is to define an accurate and reliable protocol for the EVs isolation due…
The in vitro embryo production technique (IVEP) was developed almost 40 years ago and still has some limitations that need to be overtaking, such as some diseases that can compromise the animals after birth. During this time the science and technology also had great advances that could be applied to improve IVEP. One of this is 3D bioprinting, a technique that allow the printing of struct…
(Only some records are available in English at this moment)
| 4 / 4 | Ongoing research grants |
| 8 / 8 | Completed research grants |
| 7 / 7 | Ongoing scholarships in Brazil |
| 13 / 13 | Completed scholarships in Brazil |
| 2 / 2 | Ongoing scholarships abroad |
| 4 / 4 | Completed scholarships abroad |
| 38 / 38 | All research grants and scholarships |
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