CV Lattes
Universidade Estadual Paulista (UNESP). Campus de Botucatu. Faculdade de Medicina (FMB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Dr. Janini Gomes is an Assistant Professor of Exercise Physiology in the Department of Kinesiology and Sport Management. She obtained her Ph.D. in Physiology and Pathophysiology from Sao Paulo State University in Brazil. Her research interests are centered around the relationship between chronic inflammation and oxidative stress, and their contribution to skeletal muscle atrophy. She is also interested in how exercise-mediated adaptations positively impact skeletal muscle mass regulation. (Source: Lattes Curriculum)
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Oxidative stress and imbalance between anabolic and catabolic processes are involved in heart failure-associated skeletal muscle changes. Several positive effects from aerobic exercise have been described in heart failure. However, despite recent studies reporting beneficial effects from resistive exercise, the mechanisms involved in its effects are not completely clear. Resistive exercis…
Oxidative stress is increased in skeletal muscle during heart failure (HF) and can contribute to HF-associated skeletal myopathy. However, sources of reactive oxygen species (ROS) and signaling pathways involved in ROS-induced skeletal muscle changes are not completely established. NADPH oxidase is an important source of ROS. Studies have suggested that the signaling pathways of mitogen-a…
Several chronic diseases and conditions associated with prolonged muscle inactivity can induce muscle atrophy. Regardless the cause, skeletal muscle atrophy results in muscular weakness and a decreased quality of life. Mechanical unloading that occurs with limb casting, splinting, bed rest, and spaceflight result in a substantial loss of force generating capacity, linked to a decrease in …
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