Constance Oliver

• Abstract

  Angiogenesis is a dynamic process which encompasses the formation of new blood vessels from preexisting ones. Recent studies suggest that the Notch signaling pathway may regulate the process of neovascularization. Direct contact between macrophages and endothelial cells may activate the Notch signaling pathway resulting in the spreading of endothelial cells. However, the mechanisms that r…

  Interaction between mast cells and endothelial cells during in vitro angiogenesis, AP.R

• Abstract

  Mast cells (MCs) are multifunctional immune cells implicated in inflammation, allergy, tissue repair and angiogenesis. MCs, along with neurons, melanocytes, endocrine and exocrine cells as well as other immune cells, are specialized secretory cells which present regulated secretion. The regulated secretory pathway requires the sorting of proteins to a specific route destined to secretory …

  The role of adaptor protein complex 3 (AP-3) in regulated secretion in mast cells, AP.R

• Abstract

  Under the title "Lectins - biological effects and pharmaceutical applications" we have gathered investigation projects that target the biological implications of the interactions between lectins and carbohydrates, with special emphasis on lectins involving ligands expressed on the cell surface. Because previous studies carried out by our research group revealed that lectin interactions ha…

  Lectins: biological effects and pharmaceutical applications, AP.TEM

(Only some records are available in English at this moment)

• Abstract

  Galectins are a family of lectins which share similar carbohydrate recognition domains which is responsible for ²-galactoside binding (CRDs). Galectin-1 is present both inside and outside cells, however secreted form have higher lectin activity. Galectin-1 modulates the cell adhesion and spreading, but this function depends on the cell type. Mast cells present adhesion molecules on surfac…

  Interaction between galectin-1 and integrin during adhesion and migration in mast cells, BP.PD

• Abstract

  Mast cells (MCs) are multifunctional immune cells implicated in inflammation, allergy, tissue repair and angiogenesis. Along with neurons, melanocytes, endocrine and exocrine cells, as well as other immune cells, MCs are specialized secretory cells, which presents regulated secretion. The regulated secretory pathway requires the sorting of proteins to a specific route destined to secretor…

  The involvement of the adaptor protein complex AP-3 in mast cell regulated secretion, BP.DR

• Abstract

  Mast cells are multifunctional immune cells implicated in allergy and inflammatory process. They also play a role in auto-immune, gastrointestinal diseases, cardiovascular diseases and diseases of the nervous system. Mast cells originate from an ungranulated committed mast cell precursor in the bone marrow. Granulated progenitor cells migrate through the blood stream to peripheral tissu…

  Isolation and characterization of a 110 kDa protein, a mast cell lineage marker, BP.MS

(Only some records are available in English at this moment)

• Abstract

  Mast cells are of hematopoietic origin, mainly localized at the interface between the host and the external environment that play a role in many physiological and pathological processes, which some of them are allergy, inflammation, and host response to pathogens. Mast cells are among the first cells of the immune system to interact with antigens, toxins, and pathogens, and this interacti…

  Mast cell activation through C-type lectin receptors for fungus recognition, BE.EP.DR