CV Lattes
Universidade de São Paulo (USP). Faculdade de Medicina (FM) (Institutional affiliation for the last research proposal) Birthplace: Brazil
graduate at from Faculdade de Ciências Médicas da Santa Casa de São Paulo (1970) and ph.d. from Universidade de São Paulo (1983). Has experience in Medicine, focusing on Endocrinology, acting on the following subjects: insulin receptor, diabetes melito tipo 2, insulin resistance, tyrosine kinase and exercice. (Source: Lattes Curriculum)
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On the last decade obesity is a chronicle disease which has become one of the biggest health problem on the last decades. Considered pandemic XXI century, it leads morbidity causes and early death. Affects about 1,8 billion people around the world. It is associated with other diseases, including high blood pressure , type 2 diabetes, cardiovascular risk, hyperlipidemia, obstructive sl…
Screening for genetic polymorphisms in various populations, said the gene transcription factor TCF7L2 (Transcription Factor 7-Like 2), which has a significant association with T2DM. The TCF7L2 is a potent insulin secretagogue. It was observed that polymorphic variants present in the TCF7L2 gene may result in reduced insulin secretion stimulated by the action of GLP-1 secretion. The incret…
The Metabolic Syndrome (MS) is a set of cardiovascular risk factors associated with central adiposity and insulin resistance (IR), visceral obesity as being directly responsible for IR, regarded as the pathophysiological basis of MS. The prevalence of MS is not yet well established in Brazil, but the MS is a major challenge in terms of public health, a study is essential to assist in the …
The Metabolic syndrome (MS) is a complex disorder represented by a set of cardiovascular risk factors related to central adiposity and resistance to insulin. A dietary counseling associated with lifestyle changes are considered first-choice therapies for the treatment of patients. For the dietary intervention, it is necessary to estimate the patient's basal and total metabolic rates. Ther…
Introduction- Xanthine oxidase (XO) system includes the most important enzymes involved in ROS production and it is also involved in Uric acid synthesis. Allopurinol is one of the most useful drugs in Hyperuricemia. This drug inhibits XO system, reducing plasmatic uric acid. However Allopurinol is also useful as oxidative stress inhibitor, even in average plasmatic concentration of uric a…
(Only some records are available in English at this moment)
| 6 / 2 | Completed research grants |
| 5 / 4 | Completed scholarships in Brazil |
| 11 / 6 | All research grants and scholarships |
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