Abstract
Perisylvian Syndrome (PS) is used when patients present clinical manifestations due to lesions on perisylvian or opercular region. Clinically, symptoms may vary from developmental language disturbance (DLD) to refractory epilepsy. The most frequent lesion is polymicrogyria. In previous studies, we have reported 12 families with PS and we showed that the syndrome is genetically heterogeneo…