CV Lattes
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Universidade Estadual de Campinas (UNICAMP). Faculdade de Ciências Aplicadas (FCA) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Igor Luchini Baptista in research grants and scholarships supported by FAPESP.
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The different tissues and organs of mammals have regenerative competence, differing in capacity and extent, as well as signaling or dependence on specific cells. In general, the tissue regenerative process involves the resumption of tissue functionality as well as three-dimensional reorganization of cells and extracellular matrix. In this way, investigating how satellite cells act in musc…
The skeletal muscle regenerative process is critical for tissue functional recovery after any lesion stimuli, micro-injuries or large injuries. Thus, the ability to regenerate allows the skeletal muscle to keep the homeostasis and, consequently, the whole body's health. In our previous study (under revision), we have demonstrated that in Parkin's absence, myogenic progenitor cells present…
The project shows proposals that together aim to understand the cellular and molecular mechanisms controlling the skeletal muscle regeneration, as well as the mass recovery involved in this process. On this way, the knowledge of these processes is critical to establish new therapeutic strategies, aiming to maintain the skeletal muscle function and improve in quality of life. The capacity …
Mammalian tissues and organs have regenerative properties, differing in capacity and extent, as well as signaling or dependence on specific cells. In general, the tissue regenerative process involves the resumption of tissue functionality as well as three-dimensional reorganization of cells and extracellular matrix. In muscle tissue, investigating how satellite cells act in muscle regener…
Partial hepatectomy is a technique that consists of resection of part of the liver in order to induce organ regeneration without causing damage to the remaining tissue. The liver is unique in its regenerative capacity, being able to expand its mass in order to keep meeting the body's metabolic needs. However, for regenerative processes to take place, abundant ATP is required in order to s…
Mitofaphy process, have been pointed out as a determinant for a cellular regeneration and muscle cells differentiation, an adequate and efficient way. Thus, an overexpression of Parkin, a key protein of mitofaghy process is an interesting to better elucidate the profile and Parkin pathyway in muscle cells differentiation.
The process of muscle atrophy is highly orderly and regulated. It is characterized by a reduction of muscle fiber cross sectional area and protein content, reduction of power contraction, increase of fatigability and insulin resistance. Several pathways are considered important for the loss of skeletal muscle mass, such as the ubiquitin-proteasome pathway and more recently autophagy. We h…
The process of muscle atrophy is highly orderly and regulated. It is characterized by a reduction of muscle fiber cross sectional area and protein content, reduction of power contraction, increase in fatigability and insulin resistance. Several pathways are considered important for the loss of skeletal muscle mass, such as the ubiquitin-proteasome pathway, reactive oxygen species (ROS), a…
| 1 / 1 | Ongoing research grants |
| 2 / 2 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 5 / 3 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 10 / 8 | All research grants and scholarships |
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