CV Lattes
Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
I was graduated in Biomedicine (2000-2004) in the State University of Londrina, Brazil. Following, I received a Ph.D. degree (2005-2011) and postdoctoral training (2012-2017) in Cell and Tissue Biology at the University of São Paulo, Brazil. Currently, I integrate the Placenta Lab, located in the University Hospital Jena, Germany, where I coordinate the Research Group in Endometrial and Placental Biology . Our group investigates different aspects related to endometrial decidualization, embryo implantation and placentation in normal and diabetic conditions. As models, we use human tissues, primary cells, cell lines, 3D in vitro models and an ex-vivo model of placenta perfusion. Our studies are focused on the functional characterization of non-coding RNAs expressed by endometrial and trophoblast cells and released into extracellular vesicles as well as the role of these vesicles in intercellular communication. (Source: Lattes Curriculum)
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The Laboratory of Reproductive and Extracellular Matrix Biology has been working, since your criation in 1981, to investigate the cellular and molecular adaptations of the extracellular matrix (ECM) that the uterine environment undergoes during the reproductive cycle and early pregnancy, aiming to identify and understand the necessary requirements to implantation and embryo development. O…
Our group has established a mouse model of type 1 diabetes to investigate the impact of this disease on reproduction, particularly on the uterine environment (Favaro et al., 2010, 2013, 2104; FAPESP Grants: 07/55277-6 and Doctoral Fellowship: 04/14442-6). Through this model we showed that diabetes impairs endometrial decidualization and remodeling of the decidual extracellular matrix (ECM…
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