Karina Possa Abrahão in research grants and scholarships supported by FAPESP.
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Decades of scientific studies have collected data on how alcohol (ethanol) can affect the brain. The development of new technologies has made possible the study of the effects of alcohol in specific brain pathways that are associated with the most diverse physiological functions. The lack of control over ethanol consumption is one of the main characteristics of the binge drinking and the …
Decades of scientific studies have collected data on how alcohol (ethanol) can affect the brain. The development of new technologies has made possible the study of the effects of alcohol in specific brain pathways that are associated with the most diverse physiological functions. The lack of control over ethanol consumption is one of the main characteristics of the binge drinking and the …
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The abusive use of ethanol is a public health issue and one of the major causes of death around the world. The drinking pattern is an important indicator of the probability of developing addiction and other health issues. Several factors influence ethanol drinking, including different ingredients of diets. A variable component present in commercial rodent chow is the isoflavone. Diets ric…
Alcohol (or ethanol) consumption is a serious public health problem. This drug modifies the function of brain regions related to decision-making, such as the basal ganglia. The dorsal striatum, a central nucleus of the basal ganglia, is subdivided into medial, lateral and caudal subregions. Few studies have evaluated the effects of ethanol on these dorsal striatum subregions. The striatum…
The harmful use of alcohol is not restricted to the development of dependence. When intoxicated, decision-making is impaired, which facilitates choices that may lead to risky and/or regret. Intoxication is a consequence of elevated alcohol consumption observed, for example, in "binge drinking", which is defined as the ingestion of many doses of the drug in a couple of hours. The consumpti…
According to the World Health Organization, the consumption of alcohol is one of the main causes of death worldwide. The concern with excessive alcohol has been increasing among adolescents. It is estimated that 14% of young people drink more doses and increasingly frequent. The pattern of consumption of alcohol may predict the development of problems associated with alcohol abuse and it …
Only a small percentage of alcohol users become addicted. Addicts have difficulty in changing the focus associated to the drug, perseverate on their abused drugs and struggle to learn new associations. This is due to induction of drastic changes in synaptic plasticity after repeated exposure to drugs, especially in reward systems regions as the Nucleus Accumbens. Changes in the glutamater…
Behavioral sensitization to the stimulant effect of ethanol is characterized by an increased locomotor activity observed after repeated exposure to that drug. However, there is a great variability in its development among different species and even among animals from the same strain. This variability is related to differences in dopaminergic and glutamatergic receptors, mainly in the nucl…
| 4 / 4 | Ongoing research grants |
| 3 / 3 | Ongoing scholarships in Brazil |
| 5 / 3 | Completed scholarships in Brazil |
| 12 / 10 | All research grants and scholarships |
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