CV Lattes
Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
bachelor's at Educação Física from Universidade Estadual Paulista Júlio de Mesquita Filho (2003) and doctorate at Fisiologia Humana from Universidade de São Paulo (2010). (Source: Lattes Curriculum)
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Glucose-stimulated insulin secretion (GSIS) ends with exocytosis of the insulin-containing granules, which is dependent on the recruitment and docking of the granules to the plasma membrane. Here we intend to study intracellular mechanisms important for this process, which allow the maintenance of exocytosis. Thus, the hypothesis raised herein is that the reduction of the redox state at t…
This project aims to better understand the effects of redox modulation on beta cells exocytosis and to identify the presence of redox domains in the vicinity of the plasma membrane in beta cells. Using small interference RNA (SiRNA) against p22PHOX, a NAD(P)H oxidase component, and the patch-clamp technique we will investigate the importance of this enzyme activity for the K+ membrane con…
| 1 / 1 | Completed research grants |
| 3 / 0 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 6 / 3 | All research grants and scholarships |
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