Cristina Ribeiro de Barros Cardoso

• Abstract

  Anti-TNF monoclonal antibodies are commonly used in IBD treatment. However, some patients are not responsive to this therapy and the concomitant use of this biologics with other immunosuppressive drugs that ameliorate treatment leads to important adverse effects. On the other hand, the levels of the hormone dehydroepiandrosterone (DHEA) are reduced in CD and UC patients, while the supplem…

  Immunomodulatory effects of dehidroepiandrosterone (DHEA) in the immune response of Crohn's disease patients refractory to anti-TNF treatment, AP.R

• Abstract

  Inflammmatory bowel diseases (IBD) like Crohn's disease are characterized by Th1 and Th17 exacerbated inflammatory response besides a lack of regulation by regulatory T cells (Tregs). Chronic stress is a risk factor for IBD development while the endocrine system may also play a regulatory role by producing glucocorticoids (GC) which are anti-inflammatory mediators that may induce Treg dif…

  The role of hypothalamus-pituitary-adrenal (HPA) axis and exogenous glucocorticoids in the modulation of immune response in inflammatory bowel disease, AP.JP
• Breakdown of mucosal tolerance in a novel animal model of food induced intestinal inflammation., AR.EXT

• Immunomodulatory effects of dehidroepiandrosterone (DHEA) in the immune response of Crohn's Disease patients refractory to anti-TNF treatment, BP.TT
• Dehydroepiandrosterone immunomodulative effect (DHEA) in the immune response of Crohn disease patients not responsible for antiTNF- therapy, BP.TT

• Abstract

  Toxoplasma gondii (T.gondii), a coccidian member of the Apicomplexa phylum infects approximately one-third of the world's human population. In endemic regions, especially Brazil, about 50 to 80% of the population has been exposed to T. gondii infection at least once, and cases of multiple exposures to different strains are common. The identification of molecules with therapeutic potential…

  Melatononin modulation of immune response to Toxoplasma gondii infection, BP.IC

(Only some records are available in English at this moment)