CV Lattes
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Universidade Nove de Julho (UNINOVE). Campus Vergueiro (Institutional affiliation from the last research proposal) Birthplace: Brazil
bachelor's at Ciências biológicas modalidade médica - biomédicas from Universidade de Santo Amaro (2000), master's at Pathological Anatomy and Clinical Pathology from Universidade de São Paulo (2003) and doctorate at Ciências (área de Nefrologia) from Universidade de São Paulo (2007). Has experience in Medicine, acting on the following subjects: fisiopatologia renal, fibrose renal, insuficiência renal, inflamação and tamoxifeno. (Source: Lattes Curriculum)
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Bladder cancer (BC) is one of the most common neoplasms in the world, and its non-muscle invasive form (NMIBC) is treated with resection followed by instillation with BCG. Many types of cancer produce the enzyme indoleamine 2,3-dioxygenase-1 (IDO1), which, by modulating the immune system, protects the tumor, favoring its progression. In addition to having been identified in NMICBC, IDO1 c…
Bladder cancer (BC) is among the most common urinary system. Although the most common form is the non-muscle invasive, many of these cases progress to muscle-invasive form, especially after transurethral resection which is the most used treatment. The vaccine with BCG has been used as adjuvant therapy, but a significant portion of patients still present recurrence of the disease. Indoleam…
Immune escape and metastasis are the hallmarks of several types of cancer including bladder cancer. One of the mechanisms involved in these processes has been linked to indoleamine 2,3-dioxygenase (IDO). Although IDO is classically recognized for its immunomodulatory property, it has presented nonimmunological effects in some tumors. TGF-b1 is believed to contribute to carcinoma developme…
The urogenital cancers represent a significant public health problem when the morbid-mortality is observed. One of the mechanisms involved in the pathogenesis of these cancers is the epithelial-mesenchymal transition (EMT), which correlates positively with tumor growth and metastasis, leading to a worse clinical outcome. One of the factors classically known as inducer of EMT is the TGF-be…
Bladder cancer is a common neoplasm, being the second most aggressive of the urinary tract. Its aggressiveness depends on its invasive capacity, which is linked to the process of mesenchymal epithelial transition (EMT). Indoleamine 2,3-dioxigenase-1 (IDO1) is an enzyme known for its immunomodulatory action and has been associated with TGF-²1-mediated EMT in bladder carcinoma. From the abo…
Bladder cancer (BC) is among the most common urinary system. Although the most frequent form is non-invasive, many of these cases evolve to invasive form. Indoleamine 2,3-dioxygenase (IDO) is an enzyme expressed at sites where immunomodulation is required, including the maternal-fetal interface, where the presence of IDO protects the semihalogen embryo. Because IDO is expressed in some ca…
Bladder cancer (CB) is the seventh most common cancer in men, noting that noninvasive tumors account for the largest number of cases. Transurethral resection of the bladder tumor (RRTV) associated with Bacilo Calmette-Guérin (BCG) immunotherapy is the most effective treatment and prophylaxis for non-muscle invasive tumors. Treatment with BCG is considered the best therapy, however, approx…
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing research grants |
| 8 / 3 | Completed research grants |
| 9 / 8 | Completed scholarships in Brazil |
| 18 / 12 | All research grants and scholarships |
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