graduate at Genetica from Universidade de São Paulo (1972), master's at Genetics from Universidade de São Paulo (1976) and ph.d. at Genetics from Universidade de São Paulo (1980). Has experience in Genetics, focusing on Animal Genetics, acting on the following subjects: apis mellifera, hormônio juvenil, vitellogenin, desenvolvimento and melipona quadrifasciata. (Source: Lattes Curriculum)
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The evolution of sociality in insects is associated with a major disruption in the paradigm of the trade-of between longevity and reproduction. Additionally, the fertility and contribution of the workers to colony reproduction is an area of conflict of interests between the queen and the workers and also among the workers. The stingless bees (Meliponini) are a group of particular interest…
Eusocial behavior is a recent and remarkable conquest of the Hymenoptera and is restricted to the Aculeata, a clade comprising ants, bees, and wasps. This way of life involves three pillars: overlapping generations, cooperation in care of the offspring, and division of reproductive labor. The latter presupposes division into castes, a reproductive female that can mate and lay eggs, and wo…
The insect endocrine system plays fundamental roles in modulating a range of physiological processes during the development, especially when dealing with transitions that occur in a well-defined space-time. The differential ecdysteroids and juvenile hormone titers found during the larval development and metamorphosis are examples of hormones acting to coordinate the developmental timing. …
Bees are by far the most important pollinators in both natural and agricultural ecosystems, and the recent decline of their populations poses a major threat to this equilibrium. A promising strategy to overcome or at least diminish this risk is the mass rearing of these pollinators by means of rational management techniques. These, however, require profound knowledge on these organisms …
(Only some records are available in English at this moment)
Complexes gene network of interactions are activated in response to the morphogenetic hormones: Juvenile Hormone (JH) and ecdysone, during the development of holometabolous insects. These networks are mainly consisted of transcription factors, target genes and regulators genes (miRNAs), and their activation are responsible for morphological and physiological changes which characterizes di…
The circadian clock plays essential roles in coordinating and synchronizing physiological and behavioral activities during the daily cycles and seasonal changes. It acts molecularly through the generation of circadian rhythms based on the cyclic expression of clock genes in an autoregulatory feedback loop. The current literature highlights how the knowledge about the molecular clock of or…
Two groups of bees are readily recognizable by their distinct social organization, the honey bees (Apini) and the stingless bees (Meliponini). The Apis mellifera and Scaptotrigona postica are representatives of such societies. Despite some social life-history similarities, these groups differ remarkably regarding the ovary structure and reproductive behavior aspects. In this project, we a…
The DOR gene (Diabetes and Obesity Regulated), besides being very conserved on insects and mammals, plays a role in similar molecular pathways on these two groups. In both cases, it's responsible for coding a protein that performs as a coactivator of nuclear receptors that are involved in hormonal cascades in autophagic processes and also in the insulin pathway. In mammals, DOR is known a…
(Only some records are available in English at this moment)
The nuclear receptor for Juvenile Hormone (JH) known as MET belongs to the basic helix-loop-helix Per/Arnt/Sim (bHLH-PAS) transcription factor family. It was first identified in Drosophila melanogaster where we may find a paralog called Germ-cell expressed, in Blattella germanica just the derived form is found. Despite MET being known to be a key component in the JH path, we believe it ma…
Based on regulatory function of miRNAS, the aim of Flávia's PhD project (FAPESP Process No. 2010/08332-4) is identify interactions between microRNAs and target RNAs that control female embryonic development of Apis mellifera. Thus, we built mRNAs and small RNAs libraries for five embryonic developmental phases: clivage, blastula, gastrulation, germ-band extension and retraction, and larva…
| 1 / 1 | Ongoing research grants |
| 7 / 6 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 47 / 19 | Completed scholarships in Brazil |
| 3 / 2 | Completed scholarships abroad |
| 59 / 29 | All research grants and scholarships |
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CV Lattes
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