Abstract
Quillaja brasiliensis is a tree species native to southern Brazil, popularly known as "pão-sabão", which produces bioactive triterpene saponins. Leaf saponins of Q. brasiliensis show pronounced adjuvant activity in experimental veterinary vaccines, comparable to the commercial adjuvant Quil-A®, obtained from Quillaja saponaria bark, a source that is not renewable and is at risk of imminen…