Armando Morais Ventura

• Abstract

  Respiratory syncytial virus (RSV) is the chief worldwide viral cause of severe acute respiratory tract iIIness in infants and calves. After fifty years of research, there is still no vaccine available for humans. In such context, the development of antiviral drugs with a wide spectrum is an attractive and economical alternative to vaccination. RSV is an enveloped virus and its negative st…

  Chasing cellular partners of respiratory syncytial virus, AP.R
• Human Respiratory Syncytial Virus immunization and molecular studies, AP.R

• Abstract

  Human Respiratory Syncytial Virus (HRSV) is the most important pathological agent of the respiratory tract, affecting mainly newborns and infants. It is estimated that there are 34 million new cases per year, resulting in about 200,000 deaths. Because of the large number of hospitalizations due to HRSV infection, its socioeconomic impact is considered to be a major public health burden. T…

  Functional analysis of the interaction between viral protein m and tropomyosin 3, BP.IC

• Abstract

  Human respiratory syncytial virus (HRSV) belongs to the Paramyxoviridae family and has a negative sense single stranded RNA genome, with approximately 15,000 nucleotides that encode 11 proteins. The HRSV is one of the main causes of respiratory diseases in children and newborns in the world, but also affect the elderly and people with immune deficiency. Still there are no drugs or vaccine…

  Interaction between Human Respiratory Syncytial Virus Nucleoprotein and cellular protein MAGEA11, BP.IC

• Abstract

  The Human respiratory syncytial virus (HRSV) is one of the most important pathogens of the respiratory tract, causing respiratory illness particularly in newborns, babies, children and immunocompromised patients. Until the present there is no vaccine approved or antiviral effective against the HRSV. The genome of HRSV encodes eleven proteins, being fundamental to understand its relationsh…

  Characterization of the interaction between the methylosome and the human respiratory syncytial virus nucleocapsid, BP.MS

(Only some records are available in English at this moment)

• Abstract

  This proposal aims to establish cooperation with Dr. Sabine Riffault and Dr. Jean-François Eléouët at the Department of Molecular Virology and Immunology, INRA, for training on immunization techniques and immune response analysis in a short period stage. To this end, we plan to run two experiments of immunization against hRSV. The first using DNA vaccines composed by CD8 multi epitope con…

  Immunization with DNA vaccines and hRSV n protein nanoparticles, BE.EP.IC