Professor at Veterinary Medicine Department, FZEA/USP. Graduated in Veterinary Medicine at University of São Paulo (2005) with a period at the University of Montreal (CRRA - Center de Recherche en Reproduction Animale / Faculty of Veterinary Medicine). Master in Veterinary Medicine, Animal Reproduction concentration area (2008) working with genetic modification in animals as models of study. PhD in Sciences, Animal Quality and Productivity area of the University of São Paulo (2013) focusing on the themes of cell reprogramming by gene induction into pluripotency and nuclear transfer, and stem cells in human and animal models. Awarded the CAPES Theses Award in 2014 for the thesis titled Generation of pluripotent cells through gene induction and core transfer: bovine pluripotency acquisition model. Carried out postdoctoral studies at the National Institute of Science and Technology in stem cells and cell therapy and at FZEA / USP with the study of in vitro generation of primordial germ cells and epigenetic reprogramming. Has interests and experience in developmental biology, cell reprogramming by nuclear transfer and gene induction (iPS cells), in vitro animal production and embryology, stem cells, transgenesis (genetic engineering), genetic and epigenetic technology. Full advisor at the Postgraduate Program in Anatomy of Domestic and Wild Animals (CAPES 7) of FMVZ / USP and advisor for the FCAV / UNESP - Graduate Program in Animal Reproduction. It is responsible for aYoung Researcher FAPESP grant aiming he generation of gametes and new individuals through the in vitro acquisition of pluripotency and epigenetic reprogramming, and for CAPES grant in which main objectives are the study of the pig model in translational medicine. Was responsible for CNPq Universal grant. Participant in several research projects funded by CNPq or FAPESP, including INCTC and CEPID-CTC. Member of SBTE (Brazilian Society for Embryo Technology) organizing committee 2018-2024. ResearcherID:C-6679-2012 fabianabressan@usp.br (Source: Lattes Curriculum)
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Cellular reprogramming technologies are a promising tool for the understanding of pluripotent cell biology and also to study several genetic and tissue-related disorders, enabling the investigation of the molecular events responsible for the acquisition of competency into pluri- and totipotency. This proposal aims to consolidate procedures for the generation of induced pluripotent stem (i…
Induced pluripotency cells (iPSC) have the ability to differentiate into a large number of cellsand to constitute a wide variety of tissues in both human and animal bodies. This ability todifferentiate cells allows them to be used in various economic, industrial and cutting-edgeresearch sectors, such as regenerative medicine and in vitro meat production for the foodindustry. Such studies …
The possibility of reprogramming somatic cells into induced pluripotent stem cells (iPSCs), due to their ability to differentiate into tissues of the three embryonic layers, offers an unprecedented opportunity in translational and regenerative medicine, especially for neurological disorders. In this context, it is worth highlighting Alzheimer's Disease (AD), a neurodegenerative disorder t…
Studies involving stem cells, cell therapy and regenerative medicine belong to a growing research area, with significant increase in quantity of studies that culminated with the development of induced pluripotent stem cells (iPSCs), the many different methodologies for its generation and multiple animal models. Of those, nonhuman primates, are highly relevant due to their significant gene…
Representatives of the Camelidae family of suborder Tylopoda, such as Alpacas, Guanacos, Vicunas, Llamas, Camels, Dromedaries, among others, have a strong presence in four (America, Asia, Africa, and Oceania) of the seven continents and are of great economic and social importance. due to the ability to adapt to adverse conditions, typical of the arid regions they inhabit, given their abil…
The demand for animal products is increasing globally, and in vitro technologies are great allies to accelerate the process of genetic enhancement, enabling the development of animals with higher productivity. Among the biotechnologies that can be applied, induced pluripotent stem cells (iPSCs) can contribute in several ways to the acquisition of genetically superior animals or to the dev…
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The present proposal aims for an internship at Prof. Simões-Costa laboratory (Harvard Medical School), which has been a world reference in the study of gene expression during embryonic development and, therefore, of great importance regarding stem cells and its applications for the analysis of disease models, drugs, compression of the developmental mechanisms, among others. It is proposed…
Alternative and innovative technologies in regenerative medicine are widely desirable. In vitro technologies are the key to regenerative medicine and can also be an alternative to animal protein production, enabling, for example, the development of cell-based meat an innovative technology in the food system. The main step in the in vitro study of muscle diseases requires the culture of sa…
Cell therapies are used for various purposes, mostly for clinical use and the development of improvements according to each species of interest, ranging from increased reproductive productivity in beef cattle to the precision of clinical trials for diseases in human and veterinary medicine. One of the focus techniques of study in the scientific environment is the methodology of cell repro…
Induced pluripotent stem cells (iPSCs) are pluripotent cells derived from differentiated cells that have reacquired pluripotency through expression of specific transcription factors. The process is also referred to as cellular reprogramming. This unique method has enabled us to study diseases for which it was challenging to obtain patient samples. Due to the limitations of accessing brain…
The study of embryonic stem (ES) cells provides significant advances for both cell therapy and basic sciences. However, difficulties in the adequate isolation and maintenance of ES in vitro cultures, as well as ethical and immunological barriers, are common obstacles to a practical application. The development of induced pluripotency by known transcription factors instigates new promising…
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| 41 / 34 | All research grants and scholarships |
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CV Lattes
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