CV Lattes
Universidade de São Paulo (USP). Faculdade de Medicina (FM) (Institutional affiliation from the last research proposal) Birthplace: Brazil
bachelor's at Faculdade de Medicina da Usp from Faculdade de Medicina da USP (1974), master's at Universidade de São Paulo from Universidade de São Paulo (1981) and doctorate at Universidade de São Paulo from Universidade de São Paulo (1986). Has experience in Medicine, focusing on Surgery, acting on the following subjects: nutricao, gastric bypass, indice de massa corporal, morbid obesity and nutr. parenteral. (Source: Lattes Curriculum)
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Severe obese patients with type 2 diabetes mellitus (T2DM) submitted to Roux-en-Y gastric bypass (RYGB) show significant improvement in glucose control after surgery upon discharge from the hospital, even before a considerable weight loss, with suppression of hypoglycemic drugs. Experimentally, the anatomical changes induced by RYGB can change genes expression in gastrointestinal tissue r…
Malnutrition due to liver disease is common, however, its diagnosis is difficult. The parameters used for nutritional assessment in clinical practice have limited use in this patient population. From this perspective, this study proposes to develop predictive equations for body composition for bioelectrical impedance (BIA) in cirrhotic patients. Besides being a fast and risk free method, …
The capacity to modulate inflammatory response and the metabolism of fatty acids of polyunsaturated fatty acids omega-3 (PUFA n-3) have shown benefits in controlling steatosis and the production of metabolic and inflammatory responses markers in NAFLD/NASH. The mechanisms associated with these benefits remain poorly understood. This study aims to evaluate the metabolomic profile of patien…
(Only some records are available in English at this moment)
Considered a multifactorial disease of epidemiological features, the obesity have in bariatric surgery the most effective treatment when there is no success with only clinical intervention. As invasive procedure, bariatric surgery have no complications, which include installation of postoperative nutritional deficiencies or worsening of those that were already under way. Therefore, the nu…
The analysis of microbial metabolites in fecal water has been important in elucidating the metabolic pathways related to obesity. The identification of new biomarkers that are associated with obesity to generate grants to improve the molecular understanding of this clinical condition, and learn more about the role of the intestinal microbiota in the metabolism of the host. In this perspec…
Type 2 Diabetes Mellitus (T2DM) became a worldwide epidemic with growing proportions, and obesity is an important characteristic of its development. In the therapeutic context, the Roux en Y gastric Bypass (RYGB) has been considered an effective method, capable not only of promoting weight loss, but also supporting T2DM complete resolution. Despite these clinical findings, the glycemic co…
(Only some records are available in English at this moment)
Type 2 Diabetes Mellitus (T2DM) became a worldwide epidemic with growing proportions, and obesity is an important characteristic of its development. In the therapeutic context, Roux en Y gastric Bypass (RYGB) has been considered an effective method, capable of promoting not only weight loss, but also supporting T2DM resolution. Despite these clinical findings, the glycemic control and met…
Type 2 diabetes mellitus (T2DM) is a relevant public health and obesity has been associated as the major risk factor. Roux-en-Y gastric bypass is an effective method to treat severe obesity, and its metabolic benefits lead to early and complete remission of T2DM, even before a considerable weight loss. Experimentally, the anatomical changes induced by RYGB can change genes expression in g…
Current evidence supports that n-3 PUFA, particularly EPA and DHA found in fish oil, can attenuate the development of inflammatory diseases by affecting different steps of the immune response. Their capacity to modulate eicosanoid synthesis, nuclear receptor and nuclear transcription factors activity and resolvin production may mitigate inflammatory processes already present, contributing…
| 23 / 5 | Completed research grants |
| 25 / 10 | Completed scholarships in Brazil |
| 3 / 3 | Completed scholarships abroad |
| 51 / 18 | All research grants and scholarships |
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