CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Rio Claro. Instituto de Biociências (IB) (Institutional affiliation for the last research proposal) Birthplace: Brazil
Graduated in Chemistry at the Faculdade de Filosofia Ciências e Letras de Ribeirão Preto, Universidade de São Paulo-USP (1976), Chemistry Professor at state schools and private high schools (1976-1977), Master's at Biochemistry from Universidade de São Paulo (1981), PH.D. at Genetics and Molecular Biology from Universidade Estadual de Campinas ?UNICAMP (1989) and Postdoctoral by East Carolina University School of Medicine (1997). Approved for Public Contest for Free-Teaching in Genetics (2004). Currently is Adjunct Professor at Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP) and has been worked in the areas of Biochemistry, Molecular Biology and Immunology with emphasis on the following subjects: 1) Cloning and expression of genes from Hymenoptera insect venoms (mainly wasps), biochemical and immunological characterization of recombinant allergens, 2) biochemical and molecular characterization of salivary glands of other arthropods such as ticks, 3) production and biochemical characterization of microbial enzymes. Since the beginning of all his scientific activities has been worked with over 200 authors and co-authors on papers published in journals and abstracts from congresses. (Source: Lattes Curriculum)
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Although anaphylactic shock associated with immediate hypersensitivity reactions, caused by allergenic proteins present in venoms, affects a small part of the world population, Hymenoptera stings are among the main causes of systemic allergic responses, with risk of anaphylactic shock. The order of Hymenoptera insects is very broad covering wasps, bees and ants. The immune response to th…
Polybia paulista (Hymenoptera: Vespidae) is responsible for a high number of sting accidents and anaphylaxis events in Southeast Brazil, Argentina and Paraguay. The specific detection of allergy to the venom of this wasp is often hampered by the lack of recombinant allergens currently available for molecular diagnosis. Antigen 5 (~23 kDa) from P. paulista venom (Poly p 5) is a highly abun…
The social wasp Polybia paulista (Hymenoptera, Vespidae) is quite abundant and endemic in the states of São Paulo and southern Minas Gerais. It has urban habits and is very aggressive, causing many significant accidents of medical perspective. To date, there are no allergenic extracts or components available in our country to diagnosis and treatment of allergic patients to insect venom de…
(Only some records are available in English at this moment)
(Only some records are available in English at this moment)
The social wasp Polybia paulista (Hymenoptera, Vespidae), abundant in southeastern Brazil, is extremely aggressive and responsible for many severe allergic reactions. One of the most allergenic components found in this venom is Antigen 5 (Poly p 5). Although the function of Antigen 5 has not yet been clarified, the molecule is a strong candidate to be used in immunotherapy for patients al…
| 10 / 5 | Completed research grants |
| 10 / 5 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 21 / 11 | All research grants and scholarships |
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