Abstract
This proposal is devoted to the development of methods to assess for metal contamination in fish, mainly related to tilapias (Oreochromis niloticus). By using fish bioassays, the lethal concentrations (CL50) for Cd, Cu and Cu+Cd and the respective metalothioneins (MTs) formation, as a detoxification mechanism, will be investigated. The formation and elimination of metalothioneins in organ…