Marcelo Tadeu Marin

• Translational Neuroscience and Mental Disorders, AR.EXT

• Abstract

  Ethanol addiction is a serious public health problem and current treatments for this syndrome are generally ineffective. Then new drugs are needed for this purpose. N-acetylcysteine (N-Ac) has shown efficacy in the treatment of cocaine and nicotine addiction and in pre-clinical research and pilot clinical trials. However, there is no data on the possible application of N-Ac on ethanol add…

  Neuroadaptations and behavioral alterations related to ethanol addiction: effects of N-acetylcysteine treatment in mice, AP.R

• Abstract

  Exposure to stress is related to the appearance of numerous emotional changes associated with stress. Nevertheless, not all individuals exposed to stress develop stress-related diseases. Some individuals are susceptible to stress damage, and others adapt appropriately, becoming resilient, with no changes related to depression and anxiety. In rodents, the social defeat stress (SDS) stands …

  Predictors of resilience or susceptibility to social defeat stress: the importance of coping with the aggressor and behaviors related to depression and anxiety, BP.IC

• Abstract

  Stress is a general response of the body to exposure to noxious stimuli, which, if prolonged, may lead to the development of cognitive disorders, mood disorders and cardiovascular problems. Nevertheless, not every individual exposed to stress develops diseases. This individual difference may be related to an individual's ability to adapt to aversive events, i.e. their resilience or suscep…

  Dealing with the enemy: effects of the treatment with N-acetylcysteine in the susceptibility and resilience to the social defeat stress in rats, BP.DR

• Abstract

  The contemporary lifestyle facilitates the access to psychoactive abuse substances and makes frequent the exposure to stress. This may facilitate the development of health problems by the association of stress with this substance of abuse. It is not nowadays that ethanol is a public health problem and the number of individuals who make use of this substance increasingly growing. When asso…

  Efects of N-acetylcysteine on reinstatement of the ethanol operant self-administration induced by stress in rats, BP.IC

(Only some records are available in English at this moment)

• Abstract

  Depression is a serious public health problem intrinsically related to chronic stress exposure. Nevertheless, not every individual exposed to stress develops stress-related disorders. This individual difference may be related to an individual's ability to adapt to aversive events, i.e. their resilience or susceptibility to stress. Recent studies using the animal model of social defeat str…

  Role of the ventral pallido-accumbal projections in the susceptibility to social defeat stress, BE.EP.DR