Abstract
PORTION OF RESERVE FOR TECHNICAL INFRASTRUCTURE COSTS INSTITUCIONAL SEARCH - YEAR 2022. (AU)
Sara Teresinha Olalla Saad in research grants and scholarships supported by FAPESP.
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PORTION OF RESERVE FOR TECHNICAL INFRASTRUCTURE COSTS INSTITUCIONAL SEARCH - YEAR 2022. (AU)
Bone marrow neoplasias are aggressive disorders with low healing potential. As the incidence of cancer increases with age, a growing number of older individuals are receiving therapy for cancer and frequently in intensive modalities. As these older patients tend to present comorbidities, treatment decisions can often become difficult due to their fragile physical state which may affect th…
PORTION OF THE INSTITUTIONAL TECHNICAL RESERVE FOR INFRASTRUCTURE COSTS FOR RESEARCH - EXERCISE 2023. (AU)
Application of the portion for institutional infrastructure costs for the acquisition of air conditioners (permanent material). (AU)
PORTION OF RESERVE FOR TECHNICAL INFRASTRUCTURE COSTS INSTITUCIONAL SEARCH - YEAR 2019 (AU)
(Only some records are available in English at this moment)
Myelodysplastic syndrome (MDS) is a bone marrow disease that affects the production of blood cells, with a risk of developing into acute myeloid leukemia. Treatment options are limited, highlighting the need for alternative therapies. Compounds derived from green tea, such as (-)-epigallocatechin-3-gallate (EGCG), have shown therapeutic potential in leukemia models. However, their effect …
(Only some records are available in English at this moment)
The bone marrow tumor microenvironment plays an essential role in the progression of leukemic cells. The reciprocal interaction between neoplastic, stromal, and endothelial cells, as well as the interaction of these cells with components of the extracellular matrix and soluble factors creates an environment that drives tumor development and progression, in addition to affecting the respon…
Artesunate is one of the semi-synthetic derivatives of artemisinin - active ingredient isolated from Artemisia annua L., a famous antimalarial. Recent studies show that this compound has anti-inflammatory, antileishmanial, immunomodulatory and antitumor effects. Our group showed that the treatment of transgenic mice presenting the fusion of the NUP98-HOXD13 genes, which develop Acute Myel…
Bone marrow neoplasias are aggressive disorders with low healing potential. As the incidence of cancer increases with age, a growing number of older individuals are receiving therapy for cancer and frequently in intensive modalities. As these older patients tend to present comorbidities, treatment decisions can often become difficult due to their fragile physical state which may affect th…
(Only some records are available in English at this moment)
Acute Myeloid Leukemia (AML) corresponds to a hematological neoplasm that includes the abnormal and disordered proliferation of immature blood and bone marrow (BM) cells quite common in people over 65 years of age. BM transplantation is considered the only curative treatment for AML; however, it is not applicable to most patients due to age and the presence of comorbidities. In addition, …
2 / 2 | Ongoing research grants |
33 / 20 | Completed research grants |
4 / 4 | Ongoing scholarships in Brazil |
97 / 44 | Completed scholarships in Brazil |
2 / 1 | Completed scholarships abroad |
138 / 71 | All research grants and scholarships |
Associated processes |