CV Lattes
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Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation for the last research proposal) Birthplace: Brazil
bachelor's at Bacharelado em Química from Universidade de São Paulo (2005) and doctorate at Biochemistry from Universidade de São Paulo (2010). , acting on the following subjects: bacterial motility, pilz, xanthomonas, c-digmp and eal domain. (Source: Lattes Curriculum)
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Our research group, in collaboration with researcher Dr. Edison Durigon of ICB USP, is developing a fast diagnostic tests to detect COVID-19. For this, we have already clone and express 4 fragments of the SARS-CoV-2 surface protein spike and have shown to be immonogenic against the serum of a human patient. For the production of the fast diagnostic test, proteins were produced on a large …
The goals of the project are the study of proteins of the human pathogen Leptospira interrogans. This bacterium is the causative agent of leptospirosis, a re-emerging infectious disease considered a zoonosis worldwide that affects several animals including humans. More than 500,000 cases of severe leptospirosis are reported per year, and in severe cases the patient ends up dying. Due to t…
Bacterial macromolecular protein secretion systems are large (multi-mega Dalton) multiprotein complexes that transport effector proteins through bacterial membranes to the extracellular milieu or directly into the cytoplasm of other cells. These systems also mediate the horizontal transfer of genetic material (conjugation) between bacterial cells and specialized homologous forms of these …
Leptospira interrogans serovar Copenhageni is a human pathogen that causes leptospirosis, a worldwide zoonosis. About 10% of leptospiral infections may progress to multiple organ failure and pulmonary haemorrhages leading to death. As with many other bacterial pathogens, environmental changes are sensed by L. interrogans during the course of infection and may trigger transitions between d…
Xanthomonas citri (XAC) is a phytopathogen that infects citrus trees, causing citrus canker. This bacterium possesses a secretion system that takes part in the competition for the environment, the Type IV Secretion System (T4SS), which is transmembrane machinery that contains an injection pilus responsible for the delivery of the secreted proteins into other microorganisms. One of these p…
(Only some records are available in English at this moment)
Research with bacteriophages (phages) has opened up promising perspectives for their use as antimicrobials for controlling plant, animal, and human diseases, being of special interest in an era of rising antibiotic resistance. Understanding how a phage recognizes a bacterial cell and begins the infection process is important for addressing some major challenges for these applications, par…
Bacteria and some eukaryotic organelles have nanomachines formed by large protein complexes that act in the process of secretion, in most of the cases, of macromolecules to the extracellular medium or directly into the host cell. These systems are called secretion systems and until now, were identified seven general classes of secretion systems and the chaperona/Usher system.There is a gr…
| 3 / 3 | Ongoing research grants |
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| 14 / 12 | Completed scholarships in Brazil |
| 1 / 1 | Ongoing scholarships abroad |
| 1 / 1 | Completed scholarships abroad |
| 20 / 18 | All research grants and scholarships |
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