CV Lattes
ResearcherID
ORCID
Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. Escola Paulista de Medicina (EPM) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduation at Farmácia Bioquímica from Universidade Estadual Paulista Júlio de Mesquita Filho (2001), master's at Physiology from Universidade Federal de São Carlos (2004) and doctorate at Physiology from Universidade Federal de São Carlos (2008). He is currently professor adjunto ai at Universidade Federal de São Paulo. Has experience in Pharmacology, acting on the following subjects: psicofarmacologia, drogas de abuso, nicotina, sensibilização comportamental and corticosterona. (Source: Lattes Curriculum)
| Articles published in Pesquisa FAPESP Magazine about the researcher: |
| Una potencial vacuna contra la cocaína |
| A potential vaccine against cocaine abuse |
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| News published in Agência FAPESP Newsletter about the researcher |
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| TITULO |
| Articles published in other media outlets ( ): |
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| VEICULO: TITULO (DATA) |
| VEICULO: TITULO (DATA) |
Correlational data suggests that learned associations are encoded within sparsely distributed patterns of neurons called neuronal ensembles that are selectively activated during learned behaviors. Until recently it has been difficult to prove that neuronal ensembles mediate learned behaviors because both traditional pharmacological and lesion methods, and newer optogenetic and chemo genet…
Matricellular proteins mediate interaction between cells and the extracellular matrix and are essential regulators of synaptic function and architecture. Recently, the two prototypical matricellular proteins SPARC and hevin have been implicated in depression-like behaviors, antidepressant response and resilience to stress. Studies show that hevin is induced by chronic social stress in the…
(Only some records are available in English at this moment)
Opioid Use Disorder (OUD) is associated with the chronic consumption of these substances, among which fentanyl stands out as being responsible for the highest number of overdose-related deaths worldwide. This condition is established through a conjunction of biopsychosocial factors, and its treatment presents several challenges. Among these, stress plays a crucial role in increasing patie…
The use of illicit substances, especially cocaine, has become a growing problem worldwide. Data from UNODC (2023) indicate that, in 2021, were approximately 296 million drug users, a significant increase compared to previous years. Cocaine, in particular, is a stimulant drug that has a high potential for dependence and is often associated with serious physical and mental health problems. …
The consumption of multiple psychoactive substances is a common phenomenon, particularly prevalent among those grappling with substance use disorders. Among the most concerning combinations is the simultaneous use of cocaine and alcohol, a mixture that enhances the euphoric effects of cocaine while mitigating its adversities. Despite the prevalence of this consumption pattern, its repercu…
(Only some records are available in English at this moment)
The use of cocaine represents a serious public health issue worldwide, and it is particularly concerning when it occurs during pregnancy. The exact prevalence of cocaine use during pregnancy is not fully established, but estimates suggest that approximately 1.1% of pregnant women have used this substance at some point during gestation. Epidemiological studies identify an association betwe…
Ethanol dependence is a multifactorial disorder influenced by biopsychosocial variants. In this context, exposure to stressful situations during abstinence can increase the individual's vulnerability to relapse to using this substance even after long periods. Although relevant, the neurobiology of the interaction between stress and relapse to ethanol use is still not fully understood. Thu…
Stress is an environmental risk factor for neuropsychiatric disorders. Social isolation is an example of a stressor that can impair the individual's quality of life and increase vulnerability to the development of drug use disorders. Studies show that chronic stress may alter the functioning of the hypothalamic-pituitary-adrenal (HPA) axis and that repeated exposure to stress may impair t…
(Only some records are available in English at this moment)
Alcohol Use Disorder (AUD) is a chronic condition characterized by compulsive alcohol-seeking behavior, negative impact on various aspects of life, and the development of a negative emotional state associated with withdrawal. The central amygdala (CeA) receives both pro- and anti-stress signals and plays a role in negative reinforcement processes that contribute to alcohol use and relapse…
Repeated ethanol consumption and stress are risk factors associated with the development of ethanol-use disorders, which represent a relevant public health issue that impacts millions of individuals worldwide. The D1 medium spiny neurons (MSNs) in the dorsal striatum are a neuronal subpopulation that has been implicated in responses to drugs and stress. Exposure to ethanol or stress seems…
Adolescence is an important period for neuroadaptations that contributes to the normal maturation of central nervous system. Alcohol consumption usually initiates in adolescence, and it is one of the strongest predictors for the development of an alcohol use disorders (AUDs). N-methyl-D-aspartate (NMDA) receptors (NMDARs) are present along over the stages of development and they are impli…
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing research grants |
| 6 / 6 | Completed research grants |
| 6 / 6 | Ongoing scholarships in Brazil |
| 21 / 21 | Completed scholarships in Brazil |
| 7 / 7 | Completed scholarships abroad |
| 41 / 41 | All research grants and scholarships |
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