Renê de Oliveira Beleboni

• Abstract

  Epilepsy is a neurological disorder that affects 1-2% of the world population. Preponderant factors evolved at the onset of epilepsy are cerebrovascular diseases, brain tumors and damage, drug use, genetics, and especially uncontrolled fever in early childhood. Among the most common types of epilepsy, accounting for approximately 40-60% of cases, there is the Temporal Lobe Epilepsy (TLE).…

  RNAis directed toward NMDA glutamate receptors: Neuromolecular basis of epilepsy and potential therapeutic approach., AP.R

• Abstract

  Temporal Lobe Epilepsy (TLE) is responsible for 40% of diagnosed cases of epilepsy. This type of epilepsy is in general of difficult treatment and the current therapy is characterized by occurrence of several side effects such as sedation, cognition deficit and chemical dependence, which led to partial or total impairment of patients to work. Therefore, the search of new antiepileptic dru…

  Erythrinian alkaloids from Erythrina mulungu Mart. ex Benth: general and comparative neurochemical, imunohistochemical, molecular and neuroethological analysis in rats submitted to pilocarpine seizure-induced model, AP.R

• Abstract

  The epilepsy is a widespread neurological disorder characterized by several social, economical and epidemiological implications. GABA and glutamate pathways dysfunctions play a role in several neurological disorders, including epilepsy. It has been established that a detailed understanding of these pathways and the search for new anticonvulsant drugs may provide new experimental and clini…

  Neuroethological and neurochemical characterization of alkaloids isolated from Erythrina mulungu (Leguminosae-Papilionaceae) flower hydroalcoholic extract, AP.R

(Only some records are available in English at this moment)

• Abstract

  Temporal Lobe Epilepsy (TLE) is responsible for 40% of diagnosed cases of epilepsy. TLE is the most refractory type of epilepsy when considered the different types of antiepileptic drugs (AEDs) used in the therapeutics. In addition, AEDs are currently associated to different side effects, causing the total or partial patient inability to working activity or to evolve in several types of c…

  Erythrinian alkaloids from E. mulungu Mart. ex Benth. (Leguminosae-Papilionaceae): New assessments on neuroethology, neurochemistry, histology, immunohistochemistry and electroencephalography approaches using rats submitted to pilocarpine model, BP.DR

• Abstract

  Sheep farming is in general a rustic model of livestock present in Brazil since the colonial period. Economical and social relevancies of this livestock activity are highlighted in some regions of the country. Despite a marked overall progress in the last decades, infections with the gastrointestinal parasite H. contortus represent one the most important problems in sheep production, anno…

  In Vitro and In Vivo Evaluation of antihelmintic activity of essential oils from plants of families ASTERACEAE, LAMIACEAE AND RUTACEAE against Haemonchus contortus., BP.DR