CV Lattes
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Universidade de São Paulo (USP). Faculdade de Medicina de Ribeirão Preto (FMRP) (Institutional affiliation for the last research proposal) Birthplace: Brazil
Graduate at Fisioterapia from Universidade Estadual de Londrina (1992), graduate at Physical Education from Londrina University (1987), master's at Physiology from University of São Paulo (1998) and ph.d. at Sciences from University of São Paulo (2002). Has experience in Exercise Physiology and Physiotherapy, focusing on Exercise Physiology and Cardiovascular Rehabilitation, acting on the following subjects: metabolic, cardiovascular and autonomic adaptations to physical exercise in healthy subjects and patients with chronic diseases ( hypertension, obesity, diabetes and metabolic syndrome). (Source: Lattes Curriculum)
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We will investigate women in reproductive age and after physiological menopause the effects on hemodynamics, cardiac morphofunctionality, cardiovascular autonomic control, inflammatory markers, and oxidative stress due drug (Enalapril Maleate and Losartan) treatment with different action mechanisms on renin-angiotensin aldosterone system (RAAS). We will also investigate whether the associ…
Previous studies in our laboratory have shown that rats submitted to early ovariectomy (10 weeks old) or early menopause, presented at 22 weeks of age, significant changes in the cardiac morphological and functional parameters associated with an expressive increase in fibrosis. Also observed in another study that ovariectomized rats at 10 weeks of age, when old (82 weeks old) and submitte…
(Only some records are available in English at this moment)
Menopause is resulting of an expressive reduction in ovarian hormones production during climacteric. This reduction increases the risk of the occurrence of cardiovascular diseases since these hormones influence several physiological mechanisms of regulation of body homeostasis. In this respect, it is known that these hormones, especially estrogens, positively influence cardiovascular auto…
Deprivation of ovarian hormones in young rats is marked by an important increase in cardiac fibrosis, accompanied by adverse cardiac remodeling. However, the mechanisms are still uncertain. Thus, we will investigate the involvement of the renin-angiotensin-aldosterone system (RAAS) in these findings, and whether the mechanisms involved are linked to increased activity and expression of ma…
The cholinergic stimulation through the inhibition of acetylcholinesterase (AChE) produces effects on the cardiac autonomic control that resemble those obtained through the aerobic physical training, both in humans and in experimental models. These effects are characterized mainly by significant increase in Heart Rate Variability (HRV) and in baroreflex sensitivity. However, up until now,…
Systemic arterial hypertension is pointed as one of the major risk factors to heart failure, considered one of the greatest public health problems, especially for the elderly population. Oxidative stress, sedentary lifestyle and low levels of training status have been identified as a relevant etiological factors. Thus, the purpose of this study is: evaluate the oxidative stress through qu…
(Only some records are available in English at this moment)
The multiple systemic atrophy (MSA) is a rare disease, with rapid and fatal evolution, affecting the central nervous system in different ways. It is characterized by being a ±-synucleinopathy with particularities of parkinsonism or cerebellar and pyramidal dysfunction, occurring in different combinations. However, one of the main symptoms is autonomic disfunction which is responsible for …
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