Abstract
The crotoxin is the main toxic fraction present in the venom of Crotalus durissus terrificus. This protein is a heterodimeric complex consisting of a basic phospholipase A2 (PLA2),crotoxin B (CB), associated with a chaperon and nonenzymatic subunit, crotapotina (CA). Pharmacological studies have revealed that the neuromuscular junction is a important site of action of this toxin, which ca…