Breno Esposito has a BSc in Chemistry (1994) and a MSc (1997) and PhD (2000) in Inorganic Chemistry by the Universidade de São Paulo. He was a postdoctoral fellow at the Hebrew University of Jerusalem (2000-2002) working on iron metabolism and fluorescent probes for iron. He was a visiting faculty to the University of Queensland (Australia, 2014), the Albert Einstein College of Medicine (USA, 2019-2020), and the Federal University of Pernambuco (Brazil, 2022). Currently, he is an Associate Professor at Universidade de São Paulo. He has experience in Inorganic Chemistry, Bioinorganic Chemistry, Chelation Therapy and the development of Metallodrugs. (Source: Lattes Curriculum)
| News published in Agência FAPESP Newsletter about the researcher |
| TITULO |
| Articles published in other media outlets (0 total): |
| More itemsLess items |
| VEICULO: TITULO (DATA) |
| VEICULO: TITULO (DATA) |
Bioinorganic Chemistry is an interdisciplinary area of great importance for human and animal health, as well as for the progress of ecosystems, as it deals with the metabolism of metal ions under extremely controlled conditions. In this project, we wish to combine the experience of Russian collaborator Dr Vasiliy Khripoun regarding bioavailable complexes of molybdenum and tungsten, and me…
Coral reefs are fundamental structures for aquatic ecosystems and, therefore, for cultural and economic activities. Corals are invertebrates that live in symbiosis with microalgae known as zooxanthellae, and this relationship can be affected by environmental stressors (temperature and ocean acidification), leading to the bleaching process, debilitating and even preventing the animal's sur…
Iron overload is a debilitating condition for patients, leading to decreased quality of life. At the same time, iron is a crucial nutrient also for parasites and tumor cells. Iron chelators are high affinity molecules that display several possibilities of clinical use: (i) reducing metal overload; (ii) delivering toxic metals to selected targets; (iii) scavenging essential metals from sai…
Iron overload is harmful for patients who show a significant decrease in quality of life. Simultaneously, iron is also a crucial nutrient for parasites and tumor cells. Iron chelators are high affinity molecules which have different possibilities of clinical use: (i) attenuators of metal overload; (ii) deliverers of toxic metals to selected targets; (iii) sequestrants of essential metals …
Patients undergoing myeloablative conditioning for hematopoietic stem cell transplantation (HSCT) may present iron overload due to underutilization (suppression of erythropoiesis) and release from liver and bone marrow cells (toxicity). There is a concern that forms of free and reactive iron can be involved in the occurrence of toxicity and complications commonly observed in the early set…
(Only some records are available in English at this moment)
Coral bleaching is a phenomenon that occurs when coral reefs lose their vibrant colors and become pale or white. This phenomenon is caused by the loss of symbiotic coral algae, known as zooxanthellae, which provide nutrients to corals and give them their characteristic colors. The process can be triggered by environmental stressors such as rising temperatures and ocean acidification. When…
Zooxanthellae, dinoflagellate microalgae of the Symbiodininaceae family, are symbionts of corals and other cnidarians, responsible for most of the energy metabolism of these animals. However, stress episodes such as ocean warming and/or acidification can trigger the disruption of this symbiosis (the "bleaching" of corals), with damage to coral reefs and the entire ecosystem they support. …
Candidiasis is an opportunistic mycosis that can affect several places in the body, is caused by Candida spp. Although this species lives in the microbiota of 80% of the healthy population in commensalism, when there is an imbalance in immunity, vaginal pH, or dysfunction of the intestinal microbiota, this yeast becomes pathogenic. With the increase in immunosuppressed patients, this dise…
Corals are invertebrates that live in symbiosis with microalgae of the Symbiodiniaceae family, called zooxanthellae, which provide the animals with photosynthetic products in exchange for protection and constant exposure to the sun. However, this symbiosis is sensitive to environmental impact, having recently resulted in blanching episodes (expulsion of microalgae by coral), with negative…
(Only some records are available in English at this moment)
Iron overload is responsible for a plethora of tissue damages, all of them due to the onset of labile pools of iron that include redox-active forms of this metal in the organism. Ideal ligands for iron chelation therapy should be able to penetrate the overloaded tissue, bound the metal as a stable, non-redox-active form, ferry it out from cells and transfer it to circulatory chelators (ei…
| 2 / 2 | Ongoing research grants |
| 8 / 7 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 16 / 14 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 28 / 25 | All research grants and scholarships |
| Associated processes | |
CV Lattes
ORCID