CV Lattes
Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Full Professor of Cell and Tissue Biology at the Institute of Biomedical Sciences (ICB), University of São Paulo (USP). TZ has been Vice-Dean of the ICB (1995-1998) and also Provost of for Undergraduate Studies of the USP (2010-2013). TZ is Visiting Research Fellow of the School of Medicine, Shinshu University, Japan and Honorific Visiting Professor of the Universidad de Valparaiso, Chile. TZ has the Merit Fellowship from the National Research Council (CNPq), Brazil. TZ is member of the Academy of Science of São Paulo State, Brazil, since 2008. TZ has authored 100 full articles published in international journal indexed in the ISI and has contributed in 06 book in the field of Cell and tissue Biology; Electron Microscopy, Radioautography and Animal Reproduction, including the Classic Basic Histology (Junqueira & Carneiro (The Mc Graw-Hill Companies Inc. 11 ed). The article decidualization and Implantation (j. Exp. Zool, 266, 1993) was distinguished by ISI as a Citation Classic of 90 ' years. TZ have been given more than 40 conferences as invited guest in several national and international meetings. TZ is co-author of a Highly Cited article (ISI) year?s 90 . www.biocel-icb.com.br/o.../profa-dra-telma-maria-tenorio-zorn/. (Source: Lattes Curriculum)
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During pregnancy in several species of mammals, including humans and mice, endometrial fibroblasts undergo extensive morphofunctional changes acquiring an epithelial phenotype and forming a new structure in the uterus called the decidua. In mice, the decidual reaction can be artificially induced (without the embryo), resulting in the formation of the deciduoma, a model of great relevance …
The Laboratory of Biology of Reproduction and Extracellular Matrix has been dedicated to the study of the structure and physiology of the mouse endometrium, for its importance in the maternal-fetal interface during pregnancy. Several of these functions are modulated by the ovarian sex hormones estrogen and progesterone, and hormonal imbalance may alter the reproductive cycle and impede de…
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Over the past years, the Laboratory of Reproduction and Extracellular Matrix Biology had focused their studies on the complex remodeling process of the uterine extracellular matrix (ECM) during the estrous cycle and the development of the decidua in rodents. Through many morphological studies and molecular approaches, our group demonstrated that this remodeling process includes a series o…
The Laboratory of Reproductive and Extracellular Matrix Biology has been working, since your criation in 1981, to investigate the cellular and molecular adaptations of the extracellular matrix (ECM) that the uterine environment undergoes during the reproductive cycle and early pregnancy, aiming to identify and understand the necessary requirements to implantation and embryo development. O…
Maternal hyperglycaemia is likely to be the primary cause of the fuel-mediated embryonic distress in diabetic pregnancies that damage kidney development. The functional mechanisms of kidney developmental reprogramming in diabetic pregnancies have been widely investigated, nevertheless, little is known about the alterations in the glomerular extracellular matrix (ECM) during kidney develop…
Our group has established a mouse model of type 1 diabetes to investigate the impact of this disease on reproduction, particularly on the uterine environment (Favaro et al., 2010, 2013, 2104; FAPESP Grants: 07/55277-6 and Doctoral Fellowship: 04/14442-6). Through this model we showed that diabetes impairs endometrial decidualization and remodeling of the decidual extracellular matrix (ECM…
| 22 / 15 | Completed research grants |
| 13 / 3 | Completed scholarships in Brazil |
| 3 / 2 | Completed scholarships abroad |
| 38 / 20 | All research grants and scholarships |
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