CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Botucatu. Faculdade de Medicina Veterinária e Zootecnia (FMVZ) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Bachelor's at Faculdade de Medicina Veterinária from Universidade Federal Fluminense (1992), master's at Veterinary Medicine from Universidade Estadual Paulista Júlio de Mesquita Filho (1997) and doctorate at Veterinary Medicine from Universidade Estadual Paulista Júlio de Mesquita Filho (2001). Did a pos doctoral year at the Center for Companion Animal Health, at University of California, Davis (2016/2017). Sheis is currently associate professor at Universidade Estadual Paulista Júlio de Mesquita Filho. Has experience in Veterinary Medicine, focusing on Veterinary Pathology, Comparative and translational oncology,Member of the Brazilian Veterinary Pathology Association, Brazilian Veterinary Oncology Association, Latin Comparative Pathology Group and International Coalition for Veterinary Pathology. (Source: Lattes Curriculum)
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Cancer is a common disease between humans and companion animals, and dogs are considered good natural models, since they share the same environment as humans. In animals, it is estimated that one in four dogs will develop neoplasia throughout life, and those over 10 years of age have a 50% chance of developing cancer. The therapy of choice for cancer patients is surgery, which should or s…
Dog is the only mammal species, besides men, that spontaneously develop prostatic carcinoma (PCa), related to age, androgen hormones and pre-neoplastic lesions. These prostatic lesions are frequent in men, showing similarities in the pathological and molecular aspects, in both species. For that, dog is considered a good natural model for the study of the prostate carcinogenic process. Now…
(Only some records are available in English at this moment)
Mammary neoplasms are more common in non-neutered bitches and, in these, represent about 50 to 70% of all neoplasms. Diagnosis is often late, sometimes with aggressive behavior and metastases, in addition to short survival. Given the need to classify benign and malignant neoplasms, Klopfleisch et al. (2010) confirmed through laser microdissected frozen samples that the combined expression…
Breast neoplasms are the most frequent in non-sterilized female dogs and, in these cases, they represent about 50 to 70% of all neoplasms. Diagnosis is often late, sometimes presenting aggressive behavior and metastases, in addition to short survival. Due to the need to classify benign and malignant neoplasms, in those cases where the histopathological diagnosis requires auxiliary methods…
Prostatic carcinoma is aggressive glandular neoplasia, highly metastatic in humans and canines. Usually diagnosed in dogs between 8 and 11 years old, more frequent in whole males, but can occur in neutered males. As it presents similarities in histological aspects with human prostate carcinoma and is the only species, besides man, that can occur spontaneously, the dog is a good model of c…
Neoplasms are becoming increasingly common in canine populations and humans, being responsible for high mortality rates among these populations. Furthermore, it is important to emphasize that canine neoplasms are very similar to humans, both histologically and clinically. Therefore, comparative oncology is an important tool for understanding neoplasms and developing treatment broader way.…
Prostate cancer (PC) is a common neoplasm in humans and has a similarity in clinical presentation and pathological anatomy in dogs, although, in these, it is less frequent. The dog is considered a good natural model for the study in comparative oncology and has been used for research in CP. Studies on the use of green tea in the treatment of cancer patients have been carried out since it …
The breast tumor is a frequent condition in dogs, and is a more common neoplasm in dogs, has been widely studied, mainly because it has the possibility of being used as a model for breast cancer in women, in the context of comparative oncology. The venom of the snake Crotalus der issues terrific presents a mixture of peptides, enzymes, and proteins such as Crotoxin capable of inducing the…
(Only some records are available in English at this moment)
The prostate cancer (PC) is one of the most important cancer in men worldwide. A therapeutic challenging is related to the presence of hormone-refractory tumors (HRPC). Dogs are the only mammal that develop PC with frequency and the cell of origin of canine PC still under debate. In addition, canine PC usually is androgen independent making these animals an interesting model for HRPC. Al…
GDF-15 (Growth Differentiation Factor-15) is a member of the TGF-beta family; it is also called MIC-1, PDGF-², PLAB, PDF and NAG-1. It's role in cancer is not yet clear, being reported as having a tumor suppressor or an oncogenic activity. GDF-15 was studied in different form of tumors in humans in vivo or in vitro, but in Veterinary Medicine there is only one report (Yamagushi et al., …
Mammary tumors are the most prevalent tumor in female dogs as well as in women. The study of markers that can be involved in metastatic development can help a better understanding of the carcinogenic process of this tumor, besides allow to identify prognostic markers and potential therapeutic targets that can contribute in both canine and human species. Dr Karin Sorenmo is a renowned rese…
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing research grants |
| 28 / 11 | Completed research grants |
| 3 / 3 | Ongoing scholarships in Brazil |
| 31 / 19 | Completed scholarships in Brazil |
| 4 / 4 | Completed scholarships abroad |
| 67 / 38 | All research grants and scholarships |
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