CV Lattes
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ORCID
Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. Escola Paulista de Medicina (EPM) (Institutional affiliation for the last research proposal) Birthplace: Brazil
bachelor's at Ciências Biológicas - Modalidade Médica from Universidade Federal de São Paulo (1994), master's at Pharmacology from Universidade Federal de São Paulo (1997) and doctorate at Pharmacology from Universidade Federal de São Paulo (2001). Has experience in psychobiology and neuropsychopharmacology, acting on the following subjects: learning and memory, relationship between memory and emotion and animal models for studying central nervous system disorders. (Source: Lattes Curriculum)
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Parkinson's disease (DP) is the second most prevalent age-related neurodegenerative disorder. PD comprises motor and non-motor symptoms and it's pathophysiology is related to progressive neuronal loss in the substantia nigra pars compacta. There is no known intervention that delays this progression, and at the onset of the motor symptoms, approximately 70% of the neurons have already been…
Parkinson´s disease is the second most prevalent age-related neurodegenerative disorder. The main symptoms of this pathology are severe motor deficits, but non-motor signs are also present. The pathophysiology comprises a progressive neuronal loss, and there is currently no effective intervention for slowing the degeneration. There is evidence of an important role of neuronal oxidative st…
Parkinson's disease (PD) is a motor disorder related to aging that currently affects 1-2% of the population over the age of 60, figuring as the second most common neurodegenerative disorder. Recently, the repeated treatment with low doses of reserpine (0.1 mg/kg, every other day) was validated for progressive neurochemical and behavioral alterations reminiscent of PD. For example, among o…
Parkinson's disease (PD), a chronic progressive neurodegenerative disorder, is associated with degeneration of dopaminergic neurons in substantia nigra pars compacta and striatum. In addition, several studies speculate that oxidative stress take part in reduction of dopamine levels.Although some cases of the disease can be attributed to genetic and environmental influences, the cause of m…
The Parkinson Disease (PD) is characterized as a motor disease related to aging. Nevertheless not being the most frequent neurodegenerative disease, behind only Alzheimer's disease, it currently afflicts 1-2% of the world population above 60 years old. Thus, countries with increasing life expectancy, as Brazil, consider PD an important public health burden. The epidemiology of PD involves…
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