CV Lattes
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Universidade de São Paulo (USP). Faculdade de Medicina (FM) (Institutional affiliation for the last research proposal) Birthplace: Brazil
Professor of the Faculty of Medicine of the University of São Paulo. Degree in Biological Sciences. master's degree and a doctorate in science from the University of São Paulo. He took a research internship at Harvard Medical School in Boston. She is currently a research scientist at the medical research laboratory of the urology discipline at the University of São Paulo. Has experience in the field of Cancer, molecular biology, Genetics and proteomics. (Source: Lattes Curriculum)
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Castration-resistant metastatic prostate cancer (CRPC) is an incurable disease, a large number of studies have been looking for therapeutic alternatives based on the molecular pathways that act in this phase of the neoplasia. Alterations in the androgen receptor occur frequently in the progression of this neoplasia and the androgen receptor cofactors appear as attractive molecules, since …
Prostate cancer (PC) corresponds to about 10% of all cancers, being considered the sixth most common neoplasm in the world. Due to its high prevalence, it represents an important health problem, with a strong economic impact if we consider the tracing, diagnosis, treatment and mortality due to the disease. The treatments are done according to the patient's diagnosis. In cases of high risk…
The proposed study is to analyze the expression profile of microRNAs miR-221, miR-222, miR-23b and miR27b in tissue samples from patients with prostate cancer (CaP) hormone-sensitive and hormone-resistant and also assess the roles of microRNAs and their antagomirs in CaP cell lines LNCaP and PC-3 that will suffer or no exposure to the hormone, and to evaluate the role of these microRNAs i…
Prostate cancer displays a peculiar biology with a high prevalence and low incidence clinic. The discovery and use of tumor markers have positively influenced early detection, diagnosis and staging of a number of neoplasias. The search and identification of new markers in PCa has been reason research in several laboratories, including ours (LIM 55), and promising results have been reporte…
Renal Cell Carcinoma (RCC) is a malignant, chemotherapy-resistant neoplasm that originates in the proximal contorted tubule lining of nephrons. The disease presents approximately 4% of malignancies in adults and was ranked in 2018 as the sixth deadliest cancer worldwide. RCC can be classified according to distinct genetic, molecular, and morphological features and is composed of different…
Bladder cancer is the most common cancer that affects the urinary system in the United States, responsible for thousands of deaths in both men and women. In Brazil alone, according to the Instituto Nacional de Câncer (Inca), 10,640 new cases were predicted in the year 2020. Thus, the search for new treatment methods to combat the disease, especially regarding muscle-invasive carcinoma, si…
Prostate Cancer (PC) is among the most common cancers in men around the world and causes thousands of deaths annually. One of the treatment options for localized PC is surgical removal of the organ, known as radical prostatectomy. Although surgical technique has evolved considerably in recent years, especially with less invasive techniques such as videolaparoscopy and robotic surgery, rad…
(Only some records are available in English at this moment)
Peyronies disease consists of the formation of fibrosis in the tunica albuginea of thecorpus cavernosum of the penis, which can be accompanied by pain, erectiledysfunction, and penile deformation. Its etiology is not fully understood in literature,however, it is believed that the formation of fibrous plaque is caused after recurrentmicrotrauma in the penis during the life of men with a pr…
Due to the great interest of androgen signaling in castration-resistant prostate cancer, there is an urgency to identify new molecules that may in the future serve both as biomarkers and for therapeutic purposes in prostate cancer. In this sense, the cofactors of the androgen receptor emerge as attractive molecules, since the androgen receptor manages to recruit key enzymatic cofactors fo…
Peyronie's Disease (PD) is a disease that affects about 13.1% of the entire male population worldwide, being more evident in men over 50 years. The disease is characterized by the formation of fibrous plaques in the albuminous tunic of the penis and the main signs and symptoms are pain, erectile dysfunction, and penile deformation. Today, the most accepted theory is that the disease is ca…
(Only some records are available in English at this moment)
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| 4 / 4 | Ongoing scholarships in Brazil |
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