Bachelor's at Biological Sciences from University of Sao Paulo (2000) and Doctorate in Sciences from University of Sao Paulo (2006). Experience in Molecular and Cellular Biology, Genetics, Biotechnology, Biochemistry, Protomics acting on the following subjects: control of gene expression, conditional gene expression, expression of fluorescent and bioluminescent markers and reporters in P. falciparum; prospection of potential antimalarials; protein interaction; cell signalling (Source: Lattes Curriculum)
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Despite successful efforts for its control, malaria is still a major public health problem in Brazil and in the World. The genome sequencing of several Plasmodium species as well as high through put transcriptomic and proteomic studies have allowed a better understanding about the parasite biology and its interaction with the host. In addition, thousands of compounds that inhibit parasite…
Despite successful efforts for its control, malaria is still a major public health problem in Brazil and in the World. The genome sequencing of several Plasmodium species as well as high through put transcriptomic and proteomic studies have allowed a better understanding about the parasite biology and its interaction with the host. In addition, thousands of compounds that inhibit parasite…
Conditional expression systems based of controlled protein degradation allow fast control over the expression of the gene of interest. Our previous results indicate that the fusion of a DDD, an E. coli dhfr based destabilization domain, with the FKBP derived DD more efficiently degrades the protein of interest. The aims are to confirm these results, to apply the system towards the investi…
The exit from the red blood cell (RBC) or egress is an essential step during Plasmodium falciparum erythrocytic cycle. Egress is preceded by permeabilization of parasitophorous vacuole (PV) and host cell membranes, a process regulated by signaling pathways derived from the parasite and the red blood cell and dependent on kinases, phosphatases, proteases, perforines and molecules not yet i…
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| 1 / 1 | Ongoing research grants |
| 1 / 1 | Completed research grants |
| 9 / 5 | Completed scholarships in Brazil |
| 11 / 7 | All research grants and scholarships |
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CV Lattes
ORCID