Full Professor, Department of Pathology at University of Sao Paulo Medical School.Principal investigator in Brazil for the NIH programs: "Recipient Epidemiology and Donor Evaluation Study-IV pediatric" and "Sao Paulo- Minas Gerais Neglected Tropical Disease Research Center for Biomarker Discovery".Director of the Institute of Tropical Medicine of the University of Sao Paulo from 2015 to 2019 Research focus: blood safety, Chagas disease, Sickle cell disease, HIV diversity, emerging infectious disease (Source: Lattes Curriculum)
| Articles published in Pesquisa FAPESP Magazine about the researcher: |
| Las redes brasileñas ponen su mira en las variantes del coronavirus |
| Brazilian networks keep a close eye on coronavirus variants |
| Con el genoma en la mira |
| Focus on the genome |
| El virus evoluciona |
| The evolution of a virus |
| Sangre limpia contra la fiebre amarilla |
| Clean blood against yellow fever |
| Breaking boundaries |
| Para superar fronteras |
| Articles published in Pesquisa para Inovação FAPESP about the researcher: |
| Technology reduces need for extracorporeal ventilation in patients with acute respiratory failure by 80% |
| Brazilian startup seeks to develop a wholly indigenous COVID-19 diagnostic test |
| News published in Agência FAPESP Newsletter about the researcher |
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| Articles published in other media outlets (0 total): |
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Loop-mediated isothermal amplification (LAMP) is a low-cost DNA amplification technique that is useful for low- and middle-income countries for the screening of infectious diseases. Current methods to detect the amplification assay are based on the analysis of samples using benchtop analysis tools for fluorogenic marker intensity and requires an expert to operate the device and analyze th…
Recently Brazil has been affected by unexpected arbovirus epidemics of Zika, Chikungunya, dengue and Yellow fever viruses. The huge economic burden of Zika (R$ 1 billion) and the widespread presence of mosquito vectors in Brazil highlights the need for accurate predictions of disease spread, particularly in large, densely populated regions. This UK-Brazil Partnership will enhance and expa…
COVID-19 is an acuterespiratory disease caused by the coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).In Brazil, it is a concern due to its impact on health care structures and its current mortality rate (especially in age groups above 60 years). Exponential growth of cases is expected and assessment of frequency rates such as morbidity, mortality, lethality…
Aiming at the constant improvement of the quality of scientific research activities performed at the Institute of Tropical Medicine, USP (IMT-USP), the Advisory Board of the Instituto de Medicina Tropical de São Paulo (IMT-USP), has unanimously approved the annual implementation plan for utilization of the institutional infrastructure project, supported by FAPESP, year 2018, based on a co…
Aiming at the constant improvement of the quality of scientific research activities performed at the Institute of Tropical Medicine, USP (IMT-USP), the Advisory Board of the Instituto de Medicina Tropical de São Paulo (IMT-USP), has unanimously approved the annual implementation plan for utilization of the institutional infrastructure project, supported by FAPESP, year 2017, based on a co…
(Only some records are available in English at this moment)
The Covid-19 pandemic has raised concerns regarding the use and development of screening and diagnostic models that are low-cost, highly sensitive, and widely applicable. The widespread dissemination of this virus makes it difficult to control, making mass testing of individuals an efficient measure for screening and controlling its spread. However, the high cost of tests, coupled with th…
Chikungunya fever (CF) remains an important public health problem in Brazil. Although most patients have symptoms resolution in the acute phase of the disease, 25-50% of cases progress to post-Chikungunya Chronic Inflammatory Joint Disease (pCHIKV-CIJD, post-Chikungunya Chronic Inflammatory Joint Disease), impacting directly on the quality of life of these patients. Despite causing epidem…
The availability of viral genome sequencing techniques and projections by means of mathematical, statistical, and computational models allow tracking the emergence and spread of infectious diseases on a local and global scale. Since the first confirmed case of SARS-CoV-2 infection, these techniques and analyses are responsible for an active and continuous monitoring of the epidemiological…
Viral infections of the brain tissue (Encephalitis) and inflammation of meninges (Meningitis) are processes of the Central Nervous System CNS) that can result in significant morbidity and mortality and several Viruses can be involved. Since, almost 70% of viral encephalitis cases are left without an etiologic agent identified. Arthropod-borne Viruses (ArboVirus) presents a serious challen…
(Only some records are available in English at this moment)
Recently, Brazil has been affected by unexpected and explosive epidemics of insect- transmitted viruses (arboviruses), most notably Zika, chikungunya, dengue, and yellow fever viruses. Those viruses have brought much concern in public health, and due to genetic changes, host and vector population dynamics and environmental factors, in addition to its capacity for adaptation are emerging a…
Plasma leakage is one of the main complications of dengue virus (DENV) infections and is directly related to disease severity. Dengue pathogenesis is complex and multifactorial, involving both viral and host factors. We have recently showed that contact of endothelial cells with serum from DENV-infected patients with leakage disrupts endothelial barrier function, indicated by reduction o…
The research of pathogens in blood donors can contribute significantly to improve the quality of blood products and the safety concern. Currently, blood banks (in Brazil or around the globe?), perform serological screening only for seven agents (Hepatitis, HTLV, HIV, Syphilis and Chagas). However, many other agents known or yet unidentified might be are present in samples from donors. The…
| 2 / 2 | Ongoing research grants |
| 24 / 17 | Completed research grants |
| 3 / 3 | Ongoing scholarships in Brazil |
| 34 / 27 | Completed scholarships in Brazil |
| 3 / 3 | Completed scholarships abroad |
| 66 / 52 | All research grants and scholarships |
| Associated processes | |
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