CV Lattes
Ministério da Ciência, Tecnologia e Inovações (Brasil). Centro Nacional de Pesquisa em Energia e Materiais (CNPEM) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduate at Ciências Biológicas from Universidade Estadual de Campinas (2004) and ph.d. at Genetics from Universidade Estadual de Campinas (2009). Has experience in Biochemistry, focusing on Molecular Biology, acting on the following subjects: alpha4, expression and purification, tip41, small angle x-ray scattering and saxs. (Source: Lattes Curriculum)
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The PI3K-Akt-mTOR signaling pathway is a central axis controlling cell growth, proliferation and survival. Components of this pathway are often dysregulated in cancer. Mechanistic Target of Rapamycin (mTOR) kinase is a conserved protein that plays an essential role in regulating cell growth, integrating signals of nutrient availability, growth factors, and various types of stress. The res…
The signaling pathways commonly deregulated in cancer frequently involve the PI3k-Akt-mTOR pathway. The mTOR kinase, identified as the target of rapamycin, plays an essential role in the regulation of cell growth, integrating signals from both local and systemic nutrient availability, growth factors and several types of stress. In the context of the nutrient responsive branch, the regulat…
The PP2A protein is a type of Serine/Threonine phosphatase with multiple functions in cellular physiology and signaling, mainly in apoptosis, cell cycle control and as a tumor suppressor. PP2A is a heterotrimer comprised of a catalytic subunit (C), a scaffolding subunit (A) and a variable regulatory subunit (B). The B subunit may belong to different families (B, B', B'' and B''') and each…
Living cells are constantly responding to a great variety of stimuli, which are interpreted and integrated by signaling pathways and result in a biological response - for example, differenciation, apoptosis or migration. These pathways are regulated by kinases and phosphatases. Recent large scale efforts have been made to identify and characterize kinase substrates, but phosphatase substr…
PP2A (protein phosphatase 2A), a conserved phosphoserine/-threonine specific phosphatase, is a major regulator of several cellular processes, including cell cycle, signal transduction, autophagy and metabolism. It counteracts the activation of mitogenic pathways by dephosphorylating key signaling molecules, thereby acting as an important tumor suppressor. The functional unit of PP2A is a …
| 2 / 2 | Completed research grants |
| 3 / 2 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 6 / 5 | All research grants and scholarships |
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