Abstract
Cisplatin (CDDP) is a highly effective antineoplastic agent, widely used in the treatment of various malignant tumors, including ovary, endometrium, pulmonary, bladder, head and neck, testicular, breast and colorectal cancer. Regarding CDDP-induced toxicity (mainly nephrotoxicity) considerable inter-individual differences have been reported. Several factors must be considered for differen…