CV Lattes
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ORCID
Secretaria da Saúde (São Paulo - Estado). Coordenadoria de Controle de Doenças (CCD). Instituto Adolfo Lutz (IAL) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduate of Medicine from the Universidade Federal de Pernambuco, residency in internal medicine, allergy and immunology; master of Allergy and Clinical Imunology and Ph.D. in Clinical Pathology at the Universidade de São Paulo (1999). Has experience in Immunology and Virology, acting on the following subjects:; molecular epidemiology of RNA viruses, Pathogenesis of HIV and other Retrovirus , HIV Vaccines, ARV resistance and strategies for salvage therapy. (Source: Lattes Curriculum)
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Universal HIV treatment with antiretrovirals and new forms of prevention are among the main strategies for controlling AIDS. In this scenario, patients in the acute phase of the disease are assuming even greater importance in the transmission and maintenance of the epidemic, since there is no consistent public policy for their identification and incorporation into our health system (SUS).…
Dendritic cell based immunotherapy is a potential tool to stimulate a specific immune response, as a complementary treatment for HIV-infected individuals using ART. Polarizing DCs are capable to produce high levels of IL-12p70 and induce a strong cytotoxic response that is very useful in viral infections. In this context, we propose to study aDC1 pulsed with autologous inactivated virus f…
The high rate of replication associated with low fidelity during the retrotranscription makes HIV an organism of extraordinary evolutionary speed, with some characteristics present in the early phase of infection, not observed in chronic, persistent phase, where most patients are identified. The study of this phase of infection is instrumental in epidemiological surveillance , in monitori…
The introduction of highly active antiretroviral therapy (HAART) has brought a significant decline in morbidity and an increased survival of people living with HIV/AIDS. However, during therapy, due to numerous factors, there may be selection of resistant viral strains, which compromises the action of drugs. This is a major cause of non-suppression in patients that are adherent to HAART. …
The adequate use of antiretroviral therapies by people living with HIV/AIDS is a strategic question in Public Health, essential to the control of the epidemic. Among the innovations in the area of antiretroviral medications there are agents that inhibit the binding of the virus to CCR5 co-receptors in host cells, one of the two major viral co-receptors , The efficacy of these medications …
| 2 / 2 | Ongoing research grants |
| 4 / 3 | Completed research grants |
| 12 / 2 | Completed scholarships in Brazil |
| 18 / 7 | All research grants and scholarships |
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