graduation at Odontologia from Universidade Estadual Paulista Júlio de Mesquita Filho (1989), master's at Periodontology from Universidade Estadual Paulista Júlio de Mesquita Filho (1995) and doctorate at Periodontology from Universidade Estadual Paulista Júlio de Mesquita Filho (1998). Has experience in Odontology, focusing on Periodontology, acting on the following subjects: periodontia, doença periodontal, enxertos, periodontal regeneration and biomaterials. (Source: Lattes Curriculum)
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Intraoral bone defects comprise clinical conditions caused by different factors, which are pathological, traumatic and iatrogenic. The search for regenerative methods and biomaterials that promote the resolution of bone defects and the restoration of oral functional and aesthetic conditions are fundamental for the maintenance of the health and well-being of the population. The present stu…
Over the past decades obesity has been increasing worldwide and represents a major risk factor for many chronic diseases. Meta-analyses have demonstrated that obesity is also associated with periodontitis, a bacteria-induced inflammatory disease of the tooth-supporting tissues. Obesity is characterized by excess adipose tissue, which secrets bioactive molecules called adipokines. Although…
With a high success ratio observed by the use of implants (97%), the development of new alloys and surface treatments has been the main objective in the Implantology research area. Periodontal tissue responses towards these modifications are determinant for implant integration with the human body. The proposition of this study is characterize a new titanium-molybdenum alloy with different…
Several studies have been conducted to understand distinctly the effects of periodontal diseases and of orthodontic movements on the periodontal tissues. But the effects of both processes presented together have not been fully elucidated. The aim of these in vitro and in vivo studies is to investigate the interactions of microbial and biomechanical signals on models that mimic the influe…
(Only some records are available in English at this moment)
Periodontal disease (PD) is a chronic, multifactorial inflammatory disease associated with the presence of a dysbiotic biofilm that leads to progressive loss of periodontal support tissues. Studies demonstrate how the endocannabinoid system and its receptors (CB) respond to immune responses and can be modulated in emotional situations, such as PD. Osteogenic growth peptide (OGP) and its p…
The present study aims to evaluate the pro-osteogenic effects of the phytocystatins CsinCPI-2 and CaneCPI-5, through in vitro and in vivo studies. Specifically, the in vitro study will assess the modulating impact of phytocystatins on the response of mouse bone marrow-derived macrophages (BMDMs) and on the osteoblastic differentiation of primary undifferentiated mouse bone marrow mesenchy…
The clinical failure of dental implants can occur due to inadequate osseointegration. Poor osseointegration induces mobility, inflammation, and bone resorption, leading to treatment failure. Due to systemic challenges related to insufficiency and/or poor quality of peri-implant bone tissue, which can compromise osseointegration, the development of titanium surfaces with an osteogenic and …
Osteoporosis is an osteometabolic disease, characterized by a reduction in bone mass in long bones and vertebrae, which occurs due to a decrease in estrogen levels, especially in postmenopausal women. Recently, a new drug based on an anti-sclerostin antibody (Scl-Ab) was approved for postmenopausal osteoporosis treatment. Its mechanism of action corresponds to an increase in the activity …
With the technical, scientific, and industrial advancement, the variety of surface characteristics and possibilities for the surface treatment of titanium opens an opportunity to improve its biological performance. Accelerating the osseointegration process has been investigated, in an attempt to shorten the installation of the final prosthesis and extend the longevity of rehabilitation tr…
(Only some records are available in English at this moment)
Dental implants with osteogenic potential loaded with Calcium (Ca) and Strontium (Sr) may be promising to modulate bone turnover towards osteogenesis and accelerate osseointegration. In this sense, the candidate's master's project, supported by FAPESP - process 2022/08006-7, is dedicated to evaluate the effect of the addition of Ca, Sr and osteogenic biomolecules - dexamethasone, ascorbic…
Surface treatments, development of new alloys and functionalization of implant surfaces with bioactive elements have been the objective of recent studies in the area of implant dentistry aiming to contribute to the process of osseointegration. The functionalization of the titanium surface with strontium can be performed by different methods. The purpose of this study is to compare, in vit…
Additive manufacturing is currently receiving significant attention in the field of tissue engineering and biomaterial science. The development of precise, affordable 3-dimensionally printing technologies has provided a new platform for novel research to be undertaken in 3D scaffold design and fabrication. Thus, the aim of this study will be to evaluate porcine bone marrow-derived progeni…
Many studies have been conducted to better understand the effects of periodontal disease and orthodontic tooth movement on periodontal tissues. However, the scientific literature shows no studies that assess these effects in periodontal tissues during obesity. The aim of this research project is to evaluate the effect of biomechanical force in the progression of periodontal disease in nor…
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing research grants |
| 10 / 7 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 27 / 23 | Completed scholarships in Brazil |
| 1 / 1 | Ongoing scholarships abroad |
| 5 / 5 | Completed scholarships abroad |
| 46 / 39 | All research grants and scholarships |
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