graduation at Ciências Biológicas Licenciatura Plena from Universidade Federal de Mato Grosso do Sul (1999) and doctorate at Microbiology from Universidade Federal de São Paulo (2004). Has experience in General Biology, acting on the following subjects: leiomiossarcoma uterino, via wnt and via ssh. (Source: Lattes Curriculum)
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Uterine smooth muscle tumors (USMT) arise from the myometrium and are classified according to their biological and clinical presentation as benignant, intermediary and malignant tumors. Leiomyomas (LM) are the most common benignant tumors that occurs in women at reproductive age (~70%) and their histological variants (the unconventional LM - LMU), although rare, presents clinical and morp…
Leiomyoma and leiomyosarcoma are mesenchymal tumors that occur in the uterus. These tumors have variable clinical behavior, compromising fertility and may even lead to death. Leiomyoma is a benign tumor commonly found in reproductive age women. Since leiomyosarcoma is a rare neoplasm comprising nearly 40% of the uterine sarcomas. Both leiomyosarcoma and leiomyomas are myometrial neoplasms…
(Only some records are available in English at this moment)
Uterine leiomyosarcomas are rare, aggressive and difficult to treat tumors. Given this scenario, new therapeutic approaches have been investigated. Several studies show that genetic mutations are closely associated with cellular transformation, greater metastatic potential and, consequently, worse prognosis, however, despite recent efforts, the molecular aspects of uterine leiomyosarcomas…
Among the uterine sarcomas, leiomyosarcoma (LMS) is the most common, with high rates of metastasis and relapse, even when diagnosed in early stages. It is a mesenchymal tumor that appears in the patients myometrium and presents high morbidity and mortality rates due to its clinical characteristics and histological complexity. The standard treatment for these tumors is surgery, because che…
Vulvar Squamous cell carcinoma (VSCC) corresponds 95% of vulvar tumors. Survival is determined by the commitment of the inguinal lymph nodes and it shows good prognosis when early diagnosed.Generally the uprising of these tumors in younger women is related to infection by human papilloma virus (HPV). The surgical treatment, despite being effective, can be mutilating and lead to serious ps…
Uterine sarcomas are rare mesodermal tumors that comprise approximately 3% of all cancers in this organ. They commonly show histologic diversity and aggressive behavior, with early spread and high mortality rates. Although carcinosarcomas (CS) have been reclassified recently as carcinomas, we included them in our sample for comparison purposes. Because of its diversity and rarity, there i…
(Only some records are available in English at this moment)
Leiomyoma (LM) and leiomyosarcoma (LMS) are mesenchymal tumors of uterine origin. LM and LMS are myometrial neoplasms that have the same pattern of cell differentiation, but with completely different clinical progression. Several studies have shown that aberrant activation of the Sonic Hedgehog signaling pathway (SHH) is related to the development of different types of cancer. In a previo…
| 9 / 7 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 10 / 7 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 21 / 16 | All research grants and scholarships |
| Associated processes | |
CV Lattes
ORCID