Abstract
Endogenous phospholipases A2 have a fundamental role in inflammation, neurodegenerative diseases, apoptosis and cellular senescence. Neurotoxins with PLA2 activity (beta-neurotoxins) are found in snake venoms from Elapidae and Viperidae families and these induce neuronal death. Neuronal cultures have been used as a model in order to characterize the mechanisms of action of these neurotoxi…