Priscila Gava Mazzola in research grants and scholarships supported by FAPESP.
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Burns present varying levels of tissue loss, leading to impairment of skin's functional integrity. Clinically, burns are classified in first, second and third degree lesions, according to the depth of tissue involvement. Adequate management of these lesions, mainly with the use of topical antimicrobial therapy, is of fundamental importance to avoid complications and to improve the surviva…
(Only some records are available in English at this moment)
Burns are very common injuries in society and have varying levels of tissue loss, which can compromise the skin's functional integrity. In Brazil, they are recorded among the main external causes of death, and this is mainly due to infections that evolve with septicemia. Thus, proper management of these lesions is important, and an example is topical antimicrobial therapy in order to avoi…
Baru nuts (Dipteryx alata) and chia seeds (Salvia hispanica L.) are rich in antioxidant compounds such as polyphenols, tocopherols and triterpenes, unsaturated fatty acids and triacylglycerides. The production of baru and chia oils by mechanical extraction generates waste, which could be reused for the production of plant extracts and, in this way, reduce waste and environmental impact. T…
Burns are among the most common types of tissue lesions in society, and can have several causes, such as physical, chemical, thermal and electrical agents. These lesions have varying levels of tissue loss, leading to impairment of skin's functional integrity. Clinically, burns are classified in first, second and third degree lesions, according to the depth of tissue involvement. In Brazil…
New release systems with permeation promoters for topical delivery are needed for the treatment of persistent diseases, where oral therapy causes adverse effects. Liposomes are promoters of biocompatible permeation and are successful on the market, but have the limitation of being subject to the oxidation of lipid membranes. Vegetable oils such as baru (Dipteryx alata Vog.) and chia (Salv…
Pressure Ulcers are injuries to the skin or tissue that usually occur as a result of other diseases that lead to a patient's loss of mobility, who becomes bedridden, leading to pressure in a specific area and decreased blood circulation. These lesions have different damage depth levels to the skin and can reach muscles and bones. This problem causes serious pain, impairing patients qualit…
Nanoparticles can be a carrier system of natural compounds, such as black pepper extract, effective and promising for helping and facilitating the bioavailability of compounds and encapsulated drugs. The black pepper extract is widely used in cooking, however it has a great medicinal potential already known in India for presenting healing, antioxidant, antimicrobial and antiparasitic prop…
(Only some records are available in English at this moment)
The purpose of this proposal is to develop foamable microemulsions with fluconazole and nystatin complexed with beta-cyclodextrin as active pharmaceutical ingredients. Foamable microemulsions will be characterized for their physicochemical and foaming properties, release profile and antifungal activity as novel intravaginal treatments for vulvovaginal candidiasis (VVC). Current treatments…
This study aims to design, fabricate and characterize sponges containing polysaccharide microspheres loaded with Spondias mombin L. seed extract for treatment of pressure ulcer. Pressure ulcer is a skin damage that impairs the quality of life of patients, affecting their physical, emotional, mental and social well-being. Porous biomicrospheres (beads) and sponges will be developed using c…
Cancer is a common and frequently occurring disease which seriously endangers human health, placing severe burden on economic and social development around the world. Thus, scientific community is always searching for alternatives for cancer treatment, searching for new drugs, promoting drug repositioning, or even developing new therapeutic methods and drug delivery systems. Rifamycin is …
Baru oil is produced from the nut of the barueiro fruit (Dipteryx alata), a native species from Brazil. It contains a high degree of unsaturated essential fatty acids such as oleic and linoleic, and significant amounts of zinc, ±-tocopherol and polyphenols. Due to its pharmacological effects, mainly the remarkable antioxidant activity, baru oil is an interesting candidate for medicinal us…
Skin wounds are impairments that need careful thought when it comes to choosing the best route of treatment. Each type of injury has different needs to heal properly, including an adequate dressing. Along the past decade there have been efforts to develop new types of bandages capable of delivering the required properties for proper wound healing. One of the main focus of study is the des…
(Only some records are available in English at this moment)
| 11 / 11 | Completed research grants |
| 3 / 3 | Ongoing scholarships in Brazil |
| 26 / 23 | Completed scholarships in Brazil |
| 2 / 2 | Ongoing scholarships abroad |
| 9 / 9 | Completed scholarships abroad |
| 51 / 48 | All research grants and scholarships |
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