CV Lattes
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Ministério da Educação (Brasil). Universidade Federal do ABC (UFABC). Centro de Matemática, Computação e Cognição (CMCC) (Institutional affiliation for the last research proposal) Birthplace: Brazil
graduate at Bacharelado Em Ciências da Computação from Universidade Estadual Paulista Júlio de Mesquita Filho (1990), master's at Computer Science from Universidade de São Paulo (1993) and ph.d. at Byophysics from Universidade Estadual Paulista Júlio de Mesquita Filho (2003). He is currently regeme estatutário -de at Universidade Federal do ABC. Has experience in Byophysics, focusing on Molecular Biophysics, acting on the following subjects: bioinformática, biologia estrutural, banco de dados, animação gráfica and estrutura de proteínas. (Source: Lattes Curriculum)
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A better comprehension of the molecular mechanisms that take part in several neurodegenerative illnesses (such as Alzheimer and Parkinson's disease, lateral amyotrophic sclerosis, and so on) can aid in the development of new drugs and treatments. One of the main pathologic characteristics present in all of the previously cited disorders is the present of insoluble protein aggregates. For …
Despite the great number of research in neurodegenerative diseases, these pathologies and their molecular mechanisms are not well understood nowadays. The better understanding of the molecular mechanisms involved in neurodegenerative diseases (as Parkinson's, AD, ALS, Huntington's Disease (HD), Spinal muscular atrophy (SMA)) can help the development of new drugs and treatments. Knowledg…
The thioredoxin belong to a large family of proteins whose members can interact and act upon a large number of target proteins (Meyer et al 2009). They catalyze redox reactions of disulfide bonds through an exchange mechanism dithiol disulfide (dithioldisulphide). This reaction involves a pair of cysteines separated by a pair of amino acids, which gives this family a motif (CxxC). The mai…
There are several methods/software to simulate molecular docking; those that have been implemented use different force fields and algorithms. Different approximations exist depending which type of degrees of freedom are to be considered, and this includes rigid docking where protein and ligand are rigid, semi-flexible where only a selected set of side-chains of the protein are allowed to …
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Proteins are macromolecules extremely important for the most biological processes and play a large number of functions necessary to maintain life. Many of these molecular processes involve interaction with other proteins. The protein-protein interactions (PPI) are fundamental to many biological processes and disease processes. Networks of protein-protein interactions are widely studied i…
In spite of the large amount of research conducted regarding neurodegenerative pathologies, there is still no consensus as to the cause of these pathologies from a cellular/molecular point of view. A better comprehension of the molecular mechanisms that take part in several neurodegenerative illnesses (such as Alzheimer's and Parkinson's disease, lateral amyotrophic sclerosis, and so on) …
| 1 / 1 | Ongoing research grants |
| 11 / 5 | Completed research grants |
| 6 / 1 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 19 / 8 | All research grants and scholarships |
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