CV Lattes
ResearcherID
Secretaria da Saúde (São Paulo - Estado). Coordenadoria de Controle de Doenças (CCD). Instituto Lauro de Souza Lima (ILSL) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduation at Licenciatura Em Ciências Biológicas from Universidade Estadual Paulista Júlio de Mesquita Filho (1998), master's at Genetics from Universidade Estadual de Campinas (2001) and doctorate at Genetics from Universidade Estadual de Campinas (2005). Has experience in Immunology, focusing on Immunology, acting on the following subjects: hanseníase, paracoccidioides brasiliensis, timo, atrofia tímica and apoptose. (Source: Lattes Curriculum)
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Lauro de Souza Lima Institute acts as a reference center in dermatology, developing basic, translational and applied research involving national and international partnerships for the diagnosis, control and prevention of leprosy and other skin disesaes. The resources coming from the institutional technical reserve will be used to purchase equipments that will contribute to the development…
Leprosy immunology still has many unsolved points. Although Th1 and Th2 profiles are present, respectively, in tuberculoid and lepromatous poles of disease, the factors involved in the polarization of the immune response are not known. In addition, the role of immune profiles more recently described as Treg, Th9, Th17 and Th22 are not established. Dendritic cells (DCs) are responsible by …
The activation of a cellular immune response is a crucial step in control of intracellular pathogens, including mycobacteria. Dendritic cells (DCs) play a key role in the induction and polarization of immune responses. On the other hand, DCs are instructed by different pathogens and stimuli from the environment, which influence their state of maturation and, consequently, the induction of…
The infection by Mycobacterium leprae stimulates a process of dedifferentiation and proliferation of Schwann cells (SC) which may contribute to the spread of the bacillus. SC infected with the bacillus produce mediators capable of interfering with macrophage function increasing their survival and promoting their migration. Macrophages are effector cells of the immune response that promote…
(Only some records are available in English at this moment)
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