graduate at Odontologia from Universidade Estadual Paulista Júlio de Mesquita Filho (1994), master's at Physiology from Universidade de São Paulo (1997) and ph.d. at Physiology from Universidade de São Paulo (2001). Has experience in Odontology, focusing on Bucomaxilofacial Surgery, acting on the following subjects: nts, nmda, ampa, imunocitoquímica and reparo alveolar. (Source: Lattes Curriculum)
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This project has the principal aim on evaluation of strategies that are related to the installation device (implants) that allow the improvement of repair bone in the presence of systemic condition, in pre-clinical, in vivo studies. The systemic impairment condition that will be focused on this study are osteoporosis, developed in ovariectomized rats and type 2 diabetes, developed in male…
The search for strategies that may improve the quality of bone formed around implants has involved techniques since the sophisticated design of the scrulls until the coating and treatment of their surface, in order to stimulate the activity of cells and the participation of signaling pathways that may activate responses that, in equilibrated manner, may produce bone with quality and quant…
This study will investigate the action of the association between systemic medication (oral bisphosphonate) an several medicines that will be locally applied in the surface of implants that will be installed in rat' maxilla. The medicines that will be used this study in order to functionalism the implant's surface will be Terpy (nitric oxide donator), teriparatide and genisteine. This pr…
Osteoporosis is the most common bone tissue metabolic disorder in women in the postmenopausal period, caused by estrogen deficiency. Also affects men, but in a lower incidence and usually occurs by reducing the production of testosterone, which suffer the flavoring process into estrogen. In order to understand the alveolar bone and the bone around dental implants healing behavior , thi…
(Only some records are available in English at this moment)
Around 2.2 million bone transplants are performed annually in clinical practice, which not only affects the quality of life and general health status of patients, but also represents a great economic burden for health systems. We will evaluate the regenerative potential of strontium-functionalized DNA hydrogels, through immunohistochemistry, PCR, microtomography and fluorochrome analyses,…
Biomaterials are fundamental and innovative role in Dentistry, mostly in Oral Rehabilitation, due to the search for an ideal bone substitute. Although the performance of some of thesebiomaterialsis satisfactory with good osteoconductive properties, there isessentialto improve these products, which can be done through the addition of biomolecules that can improve their properties and optim…
Since Branemark's discovery in the 1960s, osseointegrated titanium implants have been the best alternative for edentulous patients. The main objective of this project is to evaluate strategies related to the macrogeometric characteristics and surface treatment of implants that enable the improvement of reparative bone tissue in the presence of systemic compromise. The preliminary stage (i…
(Only some records are available in English at this moment)
The search for the ideal bone substitute has driven great advances in the field of Biomaterials in Dentistry. With the emergence of biomaterials that satisfactorily perform their osteoconductive role, we see the need to seek a biological improvement of these products, through the addition of biomolecules that can have a positive effect on reparative events, improving their properties. The…
Post-menopausal hormonal changes favor the onset of bone diseases such as osteoporosis, which can negatively affect bone turnover. A strategy that has been widely used with the objective of improving the bone repair process is the surface functionalization of implants, with the objective of locally adding biomolecules that can favor the repair steps. In this sense, two substances have rel…
(Only some records are available in English at this moment)
The purpose of this study is to characterize the resulting interface between bone/implant through electron microscopic analysis and evaluate the nano-osseointegration response by functionalization with Rubus coreanus in implants installed in rats submitted to ovariectomy. Sixty-four young adults female Wistar rats were used. Experimental groups are SHAM CONV, SHAM DMSO, SHAM RC 200, SHAM …
The aim of this study is to evaluate the peri-implant bone healing process by histomorphometric analysis and investigate the influences that losartan treatment may lead to peri-implant bone healing. The influence of losartan in the peri-implant bone healing will be investigated in 32 tibias of male rats; tibias was collected from 16 spontaneously hypertensive rats (SHR) and 48 normotensiv…
| 1 / 1 | Ongoing research grants |
| 6 / 6 | Completed research grants |
| 7 / 7 | Ongoing scholarships in Brazil |
| 47 / 42 | Completed scholarships in Brazil |
| 2 / 2 | Completed scholarships abroad |
| 63 / 58 | All research grants and scholarships |
| Associated processes | |
CV Lattes
ORCID