Abstract
The chelating agents Etidronate (HEDP) and Tetrasodium EDTA alkali (EDTANa4) recently were suggested as substitutes for EDTA in removing smear layer, therefore they possess the advantage they can be used mixed with sodium hypochlorite (NaOCl) in the biomechanical preparation of root canal system without compromising the dissolution of organic matter and the antimicrobial action of NaOCl. …