CV Lattes
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Universidade Federal de São Paulo (UNIFESP). Campus São José dos Campos. Instituto de Ciência e Tecnologia (ICT) (Institutional affiliation from the last research proposal) Birthplace: Brazil
MSc in Food Engineering, State University of Campinas (1980) and PhD in Chemical Engineering, University of São Paulo (1987), and Pos doc in Biodegradable Biopolymers at University of Montreal (1992). Senior Researcher of Brazilian Laboratory of Science and Technology of Bioethanol (CTBE), former R&D Advisor at Institute Butantan, former Chief of Biotechnology Laboratory at Technological Institute Reserarcher (IPT). Has experience in Chemical Engineering, focusing on Biochemical Processes, acting on the following subjects: biopolymers, polyhdroxialkanoates, vaccines production, heterologous protein expression, high-cell-density microorganism cultivation, scale-up of bioreactors. Supervisor on the Graduate Program of Biotechnology at Federal University of São Carlos - UFSCar. (Source: Lattes Curriculum)
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Monoclonal antibodies (mAbs) are a class of biotherapeutic against a range of major diseases, making a current market of $ 125 billion by 2020. The industrial production system of choice is the submerged cultivation of animal cells in large scale bioreactor. The structural complexity of mAbs, low cell growth velocity, use of complex culture media, sensitivity to temperature variations and…
The project deals with the investigation of the necessary steps to develop biotechnology for the production of bioactive substances obtained from Streptomyces. For clavulanic acid, AC and cephamycin C, CefC the study intends to fully develop complete production process alternatives including: genetic improvement, bioprocess, and bioreactor development, and also downstream processes develo…
Shiga toxin-producing Escherichia coli (STEC) strains can cause hemorrhagic colitis and hemolytic uremic syndrome by producing Shiga cytotoxin (Stx), a toxin that inhibits protein synthesis by acting on rRNA, leading to cell death. As there is no available antidote, current therapy only involves treating symptoms. Monoclonal antibody fragments have become an important class of biopharmace…
The development of sustainable technologies for the utilization of lignocelullosic biomass as those resulting from agricultural and forest activities is a part of a worldwide effort to biofuels, chemicals and energy development. In Brazil, the main biomass is sugarcane bagasse, which has several applications and it has been used in the sugar-alcohol mills to generate electricity at the sa…
The obtaining of enzymes with desirable physic-chemical characteristics at low cost is one of the major challenges in the biofuel research. Thus, the hydrolytic enzymes production by Trichoderma reesei mutant strains has been attracting interest in the industry sector. This microorganism has three positive activators (XYR1, ACE2 and HAP2/3/5 complex) and two repressors (ACE1 and CRE1) whi…
This study will assess the in silico production of omega-3, especially eicosapentaenoic acid (EPA), as a value-added product from vinasse. The United Nations recommended dietary intakes up to 500 mg / day EPA for infants in the early years of life and for adults in the prevention of cardiovascular disease, since this acid is not synthesized by humans. The use of vinasse as a carbon sourc…
| 1 / 1 | Ongoing research grants |
| 2 / 1 | Completed research grants |
| 12 / 3 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 16 / 6 | All research grants and scholarships |
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