Graduated in Biomedicine at University of Santo Amaro (2001). She completed a Direct Doctorate (2006) and Post-Doctorate (2007) at the Department of Cell and Developmental Biology at the Institute of Biomedical Sciences at University of São Paulo. The research developed in this period, addressed the role of the Renin-Angiotensin System in the development of cardiac hypertrophy promoted by the thyroid hormone, as well as the actions of these hormones in the global modulation of gene expression. She is an Associate Professor at the Federal University of ABC developing a line of research on the impact of the inflammatory response and the immune system on cardiovascular changes observed in the context of Cardiorenal Syndrome. She has experience in the areas of cell biology, molecular biology, cardiovascular physiology, inflammation and renal failure. It has scientific projects funded by FAPESP and CNPq. Coordinates extension projects aimed at courses in ethics and research integrity for high school students from public schools. From 2012 to 2014 she was academic advisor to the UFABC Research Dean, becoming UFABC's Assistant Research Dean until early 2015. Between 2015 and 2018 she was Provost for research of UFABC. (Source: Lattes Curriculum)
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In the current stage of medicine, the clinical diagnosis of a patient is obtained through the analysis of clinical examinations, comparison with standard values of physiological and genetic parameters, high-precision medical images and detection of metabolites in biofluids such as blood or urine. However, even with a broad arsenal available for characterization and measurement of homeosta…
Cardiorenal Syndrome is characterized by the presence of a systemic inflammatory condition where different clinical conditions promote cardiac and renal dysfunction. It has five different types where the first two (types 1 and 2) are associated with abnormalities in cardiac function that cause injury or renal dysfunction; the type 3 and 4 that are characterized by renal insults that subje…
The immune system interacts with several different tissues and organs of the human body, for example, the heart tissue. In diseases that generate a systemic inflammation, some factors are released in the blood stream and they are able to reach the most diverse organs, promoting interaction between tissue cells and immunity cells. It is known that renal insufficiency (RI) is characterized …
(Only some records are available in English at this moment)
The role of uremic toxins in a scenario of kidney injury has already been elucidated in literature demonstrating the effects on different tissues and their influence on inflammatory pathways. Among the various TUs currently known we have Indoxyl Sulfate (IS), a molecule formed from the amino acid tryptophan and which belongs to the class of TUs bound to proteins(PBUTs). The IS formed can …
In the current stage of medicine, the clinical diagnosis of a patient is obtained through the analysis of clinical exams, comparison with standard values of physiological and genetic parameters, high precision medical images and detection of metabolites in biofluids such as blood or urine. However, even having a wide arsenal available for characterizing and measuring homeostasis, numerous…
Cardiorenal Syndrome (CRS) is defined as a pathological relationship involving the kidneys and the heart, whose damage or injury to one of these organs is capable of leading to damage to the other organ. SCR is divided into five subtypes, according to the organ that was first injured and the period of injury (acute or chronic). SCR3 is characterized by acute kidney injury as a cause of ca…
Cardiovascular diseases (CVD) are the cause of most deaths, due not only to genetic factors, but above all, environmental factors, due to the modern lifestyle. However, they may be secondary to other diseases, such as cardiorenal syndromes (CRSs). Cardiorenal syndromes are diseases that highlight the intense connection between the functioning of the kidneys and the heart and are subdivide…
Cardiovascular diseases (CVD) are the cause of most deaths, due not only to genetic factors, but above all, environmental factors, due to the modern lifestyle. However, they may be secondary to other diseases, such as cardiorenal syndromes (SCRs). Cardiorenal syndromes are diseases that demonstrate the intense connection between the functioning of the kidneys and the heart and are subdivi…
Cardiovascular changes associated with SARS-CoV-2 have been the subject of numerous studies in the world scientific community. Patients affected by the new coronavirus have an important systemic inflammatory condition, responsible for damage to various tissues, especially heart, kidneys and vessels. Still, it is already well known that the heart and kidneys have a close relationship and a…
(Only some records are available in English at this moment)
Cardiovascular diseases are the principal cause of death in the world, they can occur for various reasons and can be secondary to other diseases, such as cardiorenal syndromes (CRS). The cardiorenal syndromes are diseases that occur between the kidneys and the heart. Type 3 cardiorenal syndrome, also known as acute renocardiac syndrome, is characterized by acute kidney injury (AKI) which …
The cardiorenal syndrome type 3 (CRS3) consists of a complex and pathological condition involving the kidney and heart, characterized by an acute cardiac injury and failure caused by acute kidney injury (AKI), mainly due to the ischemic AKI. Several mechanisms were reported to participate in the CRS3 pathophysiology, such as the well-known neurohormones hyperactivation, oxidative stress a…
The Cardiorenal Syndrome is characterized by the presence of a systemic inflammatory condition where different clinical conditions promote cardiac and renal dysfunction. It has five different types where the first two types (type 1 and 2) are associated with abnormalities in cardiac function that cause injury or renal dysfunction; those of type 3 and 4 that are characterized by renal insu…
| 9 / 5 | Completed research grants |
| 3 / 3 | Ongoing scholarships in Brazil |
| 15 / 11 | Completed scholarships in Brazil |
| 1 / 1 | Ongoing scholarships abroad |
| 2 / 2 | Completed scholarships abroad |
| 30 / 22 | All research grants and scholarships |
| Associated processes | |
CV Lattes
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