graduate at Farmácia e Bioquímica from Universidade de São Paulo (1989) and ph.d. at Biochemistry from Universidade de São Paulo (1995). Has experience in Biochemistry, focusing on Biochemistry, acting on the following subjects: trypanosoma, phage display, doença de chagas, tc-85 and adesão. (Source: Lattes Curriculum)
| Articles published in Pesquisa FAPESP Magazine about the researcher: |
| Biochemists identify retinal changes associated with blindness in preterm infants |
| Unraveling the web |
| Para desenredar la trama |
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| News published in Agência FAPESP Newsletter about the researcher |
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| TITULO |
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Blood vessels play a central role in the most diverse physiological and pathological processes. Over the past few years, our group has been studying two important aspects of vascular biology: the process of formation of new blood vessels by angiogenesis and the molecular heterogeneity of vascular networks in different organs and tissues of the body. Understanding the molecular mechanisms …
The concept of vascular heterogeneity is well accepted by the scientific community, playing an essential role in physiological and pathological processes. Since blood vessels are important in organogenesis, differentiation, and morphogenesis of tissues and organs, it becomes interesting to unveil the cerebral vascular diversity, identifying new molecular markers for such important organ. …
Angiogenesis, the formation of new blood vessels from pre-existing ones, is an important process in vertebrate organisms, in physiological and pathological conditions. Retinopathy, a primary reason for legal blindness in adults, is an example in which angiogenesis has a key role in disease formation and progression. Macular degeneration and diabetic and retinopathy of prematurity are dis…
Angiogenesis is the formation of new blood vessels from pre-existing ones and it is an important process in health and disease. Examples in which angiogenesis participate in disease are cancer and retinopathy, a important cause for blindness in adults. Retinopathy of prematurity or in diabetes, as well as macula degeneration have an important angiogenic component. These diseases afflict p…
(Only some records are available in English at this moment)
"Angiogenesis-dependent diseases", such as cancer and retinopathies, affect a large number of individuals. In addition to the suffering of these individuals, these diseases cause great socioeconomic impacts. In this context, the pharmaceutical industry has been committed to developing drugs with anti-angiogenic activity, especially with anti-VEGF activity. Although great strides have been…
(Only some records are available in English at this moment)
Chagas' disease, caused by the parasite Trypanosoma cruzi, affects 7 to 8 million people worldwide. The condition can be debilitating, and even life-threatening, to those that develop cardiomyopathy or one of the digestive forms of the disease, making it a significant burden to health care and society at large. Treatment options for patients are still limited to two drugs, both of them wi…
Angiogenesis is the process of blood vessels formation from preexisting vessels. Angiogenesis is important for physiological and pathological processes, such as cancer and retinopathy. Current anti-angiogenic therapies affect the homeostasis of normal blood vessels. Therefore, it is important to better understand the molecular mechanisms of angiogenesis as such knowledge might help the d…
| 1 / 1 | Ongoing research grants |
| 5 / 4 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 20 / 18 | Completed scholarships in Brazil |
| 3 / 2 | Completed scholarships abroad |
| 30 / 26 | All research grants and scholarships |
| Associated processes | |
CV Lattes
ORCID